Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/4917
Title: Acute effects of automated continuous positive airway pressure on blood pressure in patients with sleep apnea and hypertension
Authors: Dursunoglu, Neşe
Dursunoglu, Dursun
Çuhadaroglu, Ç.
Kiliçaslan, Z.
Keywords: Automated continuous positive airway pressure therapy
Blood pressure monitoring
Heart rate
Hypertension
Sleep apnea
adult
article
automation
blood pressure
blood pressure monitoring
clinical article
clinical trial
controlled clinical trial
controlled study
diastolic blood pressure
disease severity
heart beat
heart rate
hemodynamic parameters
human
hypertension
night
polysomnography
positive end expiratory pressure
priority journal
sleep apnea syndrome
systolic blood pressure
Blood Pressure
Blood Pressure Monitoring, Ambulatory
Circadian Rhythm
Continuous Positive Airway Pressure
Follow-Up Studies
Heart Rate
Humans
Middle Aged
Polysomnography
Sleep Apnea Syndromes
Treatment Outcome
Abstract: Background: The obstructive sleep apnea-hypopnea syndrome (OSAHS) is characterized by repetitive upper airway obstructions during sleep, and it might cause cardiovascular complications such as myocardial infarction, arrhythmias, and systemic and pulmonary hypertension. Objectives: We investigated the acute effects of automatic continuous positive airway pressure (automated CPAP) on blood pressure in patients with OSAHS and hypertension. Methods: Polysomnography was used and ambulatory blood pressure measurements were done in 12 patients with OSAHS. Blood pressure and heart rate were measured at night (10 p.m. to 6 a.m.) and during the day (6 a.m. to 10 p.m.). During these periods systolic, diastolic and mean blood pressure and heart rate of the patients on the diagnostic day were compared with those on the treatment day. Results: Patients had moderate or severe OSAHS; their mean age was 52.8 ± 4.2 years. Systolic, diastolic and mean blood pressure and heart rate between the diagnostic and treatment day were not significantly different. Standard deviations of all these parameters during the night of the treatment day (9.1 ± 4.5, 7.5 ± 3.3, 8.0 ± 3.0 mm Hg, and 4.8 ± 1.5 beats/min, respectively) were significantly lower than during the night of the diagnostic day (12.6 ± 4.9 mm Hg, p = 0.023, 10.8 ± 3.5 mm Hg, p = 0.004, 11.6 ± 4.4 mm Hg, p = 0.006 and 6.9 ± 1.6 beats/min, p = 0.003, respectively). We did not find similar results during daytime periods. Conclusions: Automated CPAP therapy in patients with sleep apnea and hypertension did not decrease systolic and diastolic blood pressures and heart rates acutely. However, it might reduce the variability of these parameters during sleep in patients, but not during the day. It might be suggested that automated CPAP reduces cardiovascular morbidity of OSAHS via stabilizing heart rate and blood pressure during sleep. Copyright © 2005 S. Karger AG.
URI: https://hdl.handle.net/11499/4917
https://doi.org/10.1159/000084045
ISSN: 0025-7931
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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