Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/4945
Title: Obstructive sleep apnea syndrome, endothelial dysfunction and coronary atherosclerosis
Authors: Dursunoğlu, Neşe
Dursunoğlu, Dursun
Keywords: adrenergic system
anoxia
coronary artery atherosclerosis
hospitalization
human
hypertension
oxidative stress
pathophysiology
review
risk factor
sleep apnea syndrome
vascular endothelium
Anoxia
Coronary Arteriosclerosis
Endothelium, Vascular
Humans
Hypertension
Oxidative Stress
Risk Factors
Severity of Illness Index
Sleep Apnea, Obstructive
Sympathetic Nervous System
Abstract: In obstructive sleep apnea syndrome (OSAS), repetitive episodes of apnea cause increased sympathetic nerve activity, increased surges in arterial blood pressure, swings in intrathoracic pressure, oxidative stres, hypoxia and hypercapnia. The association of OSAS with some diseases, having endothelial dysfunction in their physiopathology, such as hypertension, diabetes mellitus, obesity, coronary artery diseases, stroke and heart failure is common. Increased sympathetic nerve activity and also endothelial dysfunction which are the results of hypoxia, have important roles in vascular complications of OSAS. When compared with healthy population, an important endothelial dysfunction in OSAS patients and relationship between OSAS severity and endothelial dysfunction have been shown. In this review, the relationship between OSAS and endothelial dysfunction was overviewed.
URI: https://hdl.handle.net/11499/4945
ISSN: 0494-1373
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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