Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/5005
Title: Immunohistochemical detection of 1,25-dihydroxyvitamin D receptor in rat vaginal epithelium
Authors: Yıldırım, Başak
Abban, Gülçin
Erdogan, B.S.
Keywords: epithelium
receptor
Vagina
vitamin D
vitamin D receptor
animal tissue
article
basal cell
cell differentiation
cell proliferation
controlled study
diestrus
estrus
estrus cycle
female
immunohistochemistry
nonhuman
ovariectomy
priority journal
proestrus
protein analysis
protein expression
protein function
protein localization
rat
vagina epithelium
Animals
Cell Differentiation
Cell Division
Epithelial Cells
Epithelium
Estrus
Female
Immunohistochemistry
Ovariectomy
Rats
Rats, Inbred Strains
Receptors, Calcitriol
Tissue Distribution
Abstract: To determine the distribution of 1,25-dihydroxyvitamin D receptor (VDR) in rat vaginal epithelium during the estrus cycle and in ovariectomized rats. Animal study performed in two groups of rats. The expression of VDR was examined in the first group during the estrous cycle and in the second group after ovariectomy. University animal laboratory. Balb/c female rats. Vaginas were removed and processed for immunohistochemical analysis. We recorded the localization, distribution, and expression of VDR in vaginal epithelium during the rat estrus cycle and in ovariectomized rats. In cyclic rats, VDR was detected in basal and suprabasal cells during all of the cycle periods. In apical cells, VDR was positive in diestrus and estrus but negative in proestrous. In ovariectomized rats, VDR was not detected in any layers of vaginal epithelium. In vaginal epithelium, the presence of VDR was shown by using immunohistochemical techniques. During the estrous cycle, VDR has an important role in the proliferation and differentiation of vaginal squamous epithelium that is similar to the effects of estrogen. © 2004 by American Society for Reproductive Medicine.
URI: https://hdl.handle.net/11499/5005
https://doi.org/10.1016/j.fertnstert.2004.07.949
ISSN: 0015-0282
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

Show full item record



CORE Recommender

SCOPUSTM   
Citations

13
checked on Dec 14, 2024

WEB OF SCIENCETM
Citations

11
checked on Dec 20, 2024

Page view(s)

28
checked on Aug 24, 2024

Google ScholarTM

Check




Altmetric


Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.