Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/50468
Title: Cognitive function and cardiorespiratory fitness affect gait speed in type-2 diabetic patients without neuropathy
Authors: Fındıkoğlu, Gülin
Altınkapak, Abdurrahim
Alkan, Hakan
Yıldız, Necmettin
Şenol, Hande
Ardıç, Füsun
Keywords: Older-Adults
Blood-Pressure
Walking Speed
Health
Pain
Determinants
Dysfunction
Nutrition
Mellitus
Strength
Publisher: Medicinska Naklada
Abstract: Aim To identify physical, cognitive, and metabolic factors affecting gait speed in patients with type-2 diabetes mellitus (T2DM) without neuropathy. Methods This cross-sectional study enrolled 71 diabetic patients without neuropathy (mean age 55.87 +/- 7.74 years, 85.9% women). Neuropathy status was assessed with Douleur Neuropathique 4. We used a cut-off point for gait speed of 1 m/s to classify the participants into two groups: slow walkers (SW) and average and brisk walkers (ABW). The groups were compared in terms of age, sex, body mass index (BMI), hemoglobin A1c (HbA1c), fasting glucose, systolic blood pressure, maximal aerobic capacity (VO2 max), percentage of muscle mass, percentage of lower extremity muscle mass, Mini-Mental State Examination (MMSE) score, and years of education. Results Compared with the ABW group, the SW group had significantly lower VO(2)max (14.49 +/- 2.95 vs 16.25 +/- 2.94 mL/kg/min) and MMSE score (25.01 +/- 3.21 vs 27.35 +/- 1.97), fewer years of education, and these patients were more frequently women (P < 0.05). In the multivariate regression models, the combination of VO2 max, sex, and MMSE score explained only 23.5% of gait speed (P < 0.001). MMSE score and VO2 max independently determined gait speed after adjustment for age, BMI, HbA1c, fasting glucose, systolic blood pressure, percent of muscle mass, percent of lower extremity muscle mass, and years of education. Conclusion In diabetic patients without neuropathy, physical impairment and disability could be prevented by an improvement in aerobic capacity and cognitive function.
URI: https://doi.org/10.3325/cmj.2022.63.544
https://hdl.handle.net/11499/50468
ISSN: 0353-9504
1332-8166
Appears in Collections:Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

Files in This Item:
File SizeFormat 
CroatMedJ_63_0544.pdf696.39 kBAdobe PDFView/Open
Show full item record



CORE Recommender

Page view(s)

56
checked on Aug 24, 2024

Download(s)

22
checked on Aug 24, 2024

Google ScholarTM

Check




Altmetric


Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.