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https://hdl.handle.net/11499/50482
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Turhan, Gürkan | - |
dc.contributor.author | Çil, Nazlı | - |
dc.contributor.author | Kabukçu, Cihan | - |
dc.contributor.author | Turan, Tahir | - |
dc.contributor.author | Fenkci, İbrahim Veysel | - |
dc.contributor.author | Abban Mete, Gülçin | - |
dc.date.accessioned | 2023-04-08T10:01:04Z | - |
dc.date.available | 2023-04-08T10:01:04Z | - |
dc.date.issued | 2022 | - |
dc.identifier.issn | 2148-9580 | - |
dc.identifier.uri | https://doi.org/10.4274/jus.galenos.2022.2021.0121 | - |
dc.identifier.uri | https://hdl.handle.net/11499/50482 | - |
dc.description.abstract | Objective: This study examines the relationship between seminal plasma anti-Mullerian hormone (AMH) levels and sperm morphology and sperm DNA fragmentation.Materials and Methods: Semen and blood samples were obtained from volunteers. There were four patient groups that are normozoospermia (n=46), oligoasthenoteratozoospermia (n=18), azoospermia (n=19) and teratozoospermia (n=68), based on semen analysis results. Serum follicle -stimulating hormone, luteinizing hormone, testosterone, serum and seminal plasma AMH levels were measured. DNA fragmentation of sperm was assessed by the TdT-mediated dUTP nick-end labeling (TUNEL) test.Results: Azoospermic group showed the highest blood AMH levels. The seminal AMH level of normozoospermic patients was found to be significantly lower compared to the oligoasthenoteratozoospermia group. No significant associations between seminal AMH, sperm morphology, and sperm DNA damage were observed. No significant difference was observed among the groups regarding sperm DNA fragmentation.Conclusion: A large number of TUNEL-positive cells in normozoospermic patients demonstrates that DNA damage of sperm may also occur in normal sperm parameters individuals. The measurement of serum and seminal AMH levels does not provide any additional benefit during the evaluation of male infertility. | en_US |
dc.description.sponsorship | Pamukkale University Scientific Research Projects Coordination Unit [2018SABE013] | en_US |
dc.description.sponsorship | This study was supported by the Pamukkale University Scientific Research Projects Coordination Unit through project numbers 2018SABE013. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Galenos Publ House | en_US |
dc.relation.ispartof | Journal of Urological Surgery | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Sperm | en_US |
dc.subject | seminal plasma | en_US |
dc.subject | anti-m?llerian hormone | en_US |
dc.subject | TUNEL | en_US |
dc.subject | Mullerian-Inhibiting Substance | en_US |
dc.subject | Tunel Assay | en_US |
dc.subject | Fragmentation | en_US |
dc.subject | Men | en_US |
dc.subject | Spermatogenesis | en_US |
dc.subject | Integrity | en_US |
dc.subject | Marker | en_US |
dc.subject | Males | en_US |
dc.title | Relationship of Seminal Plasma Anti-Müllerian Hormone Concentration with Sperm Morphology and Sperm DNA Damage | en_US |
dc.type | Article | en_US |
dc.identifier.volume | 9 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.startpage | 272 | en_US |
dc.identifier.endpage | 280 | en_US |
dc.department | Pamukkale University | en_US |
dc.identifier.doi | 10.4274/jus.galenos.2022.2021.0121 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.trdizinid | 1175690 | en_US |
dc.identifier.wos | WOS:000899386100008 | en_US |
dc.institutionauthor | … | - |
item.fulltext | With Fulltext | - |
item.grantfulltext | open | - |
item.languageiso639-1 | en | - |
item.openairetype | Article | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.author.dept | 14.03. Basic Medical Sciences | - |
crisitem.author.dept | 14.01. Surgical Medicine | - |
crisitem.author.dept | 14.01. Surgical Medicine | - |
crisitem.author.dept | 14.01. Surgical Medicine | - |
crisitem.author.dept | 14.03. Basic Medical Sciences | - |
Appears in Collections: | Tıp Fakültesi Koleksiyonu TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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File | Size | Format | |
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JUS-9-272-En.pdf | 812.01 kB | Adobe PDF | View/Open |
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