Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/50508
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dc.contributor.authorGök, Soner-
dc.contributor.authorAlataş, Erkan-
dc.date.accessioned2023-04-08T10:01:57Z-
dc.date.available2023-04-08T10:01:57Z-
dc.date.issued2022-
dc.identifier.issn2168-8184-
dc.identifier.urihttps://doi.org/10.7759/cureus.31721-
dc.identifier.urihttps://hdl.handle.net/11499/50508-
dc.description.abstractObjective This study aimed to investigate the effects of levonorgestrel-releasing intrauterine device (LNG-IUD) treatment on ovarian reserve in women of reproductive age diagnosed with menorrhagia.Methods This was a prospective controlled trial involving 50 women with menorrhagia and a control group comprising age-matched 50 healthy women. Women who satisfied the LNG group criteria underwent an endometrial pipelle biopsy and LNG-IUD insertion. Ovarian reserve tests were performed prior to and six months after LNG-IUD insertion in the LNG group cases.Results Follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), anti-Mullerian hormone (AMH), endometrial thickness (ET), total antral follicle count (AFC), and mean ovarian volume values before LNG-IUD insertion did not differ between the LNG and control groups. When the final measurements were compared, FSH, AMH, total AFC, and average ovarian volume increased (p=0.05, 0.046, 0.022, and 0.022, respectively), E2 and ET decreased (p=0.034 and 0.001, respectively) in the LNG group, while LH did not differ significantly between the groups (p=0.71). Conclusion We observed that LNG-IUD use effectively improves fertility capacity. In this study, LNG-IUD use in reproductive-age women diagnosed with menorrhagia decreased E2 levels, did not change LH levels, and increased FSH, AFC, and AMH levels.en_US
dc.language.isoenen_US
dc.publisherCureus Incen_US
dc.relation.ispartofCureus Journal of Medical Scienceen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjecttherapyen_US
dc.subjectovarian reserveen_US
dc.subjectmenorrhagiaen_US
dc.subjectlevonorgestrel-releasing intrauterine deviceen_US
dc.subjectanti-m?llerian hormoneen_US
dc.subjectAnti-Mullerian Hormoneen_US
dc.subjectAmhen_US
dc.subjectWomenen_US
dc.subjectMenopauseen_US
dc.subjectSystemen_US
dc.subjectTestsen_US
dc.titleEffects of Levonorgestrel-Releasing Intrauterine Device Therapy on Ovarian Reserve in Menorrhagiaen_US
dc.typeArticleen_US
dc.identifier.volume14en_US
dc.identifier.issue11en_US
dc.departmentPamukkale Universityen_US
dc.identifier.doi10.7759/cureus.31721-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.pmid36569727en_US
dc.identifier.wosWOS:000895308700035en_US
dc.institutionauthor-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextopen-
item.languageiso639-1en-
item.openairetypeArticle-
item.fulltextWith Fulltext-
item.cerifentitytypePublications-
crisitem.author.dept14.01. Surgical Medicine-
crisitem.author.dept14.01. Surgical Medicine-
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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