Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/50725
Title: Optimal screening value of vitamin D deficiency for distal symmetric polyneuropathy in patients with diabetes
Authors: Kaymaz, Serdar
Aykan, Sanem Aslıhan
Abstract: Abstract Aim: The cut-off value of serum 25-hydroxy-vitamin D level for bone-skeletal and cardiovascular diseases are well defined. However, there is no current study defining the optimal cut-off value of serum 25(OH)D levels for preventing diabetic distal symmetric polyneuropathy (DSP). We aimed to evaluate the relationship between the 25(OH)D levels and the parameters of electrophysiology and Toronto Clinical Scoring System (TCSS) to obtain a cut-off value of serum 25(OH)D levels in diabetic DSP patients. Materials and Methods: This is a case-control study included 90 diabetic patients with or without diagnosed DSP who were visiting the outpatient Physical Therapy and Rehabilitation Clinic. The patients’ demographic data and vitamin D levels were recorded. The patients were classified according to serum 25(OH)D levels as having optimal, insufficiency, and deficiency. The electrophysiological study was conducted for the diagnosis and staging of polyneuropathy. TCSS was used to evaluate the patients’ neuropathic symptoms. Results: From the results of this study conducted on the 90 patients that were diagnosed with diabetes, it was found that the electrophysiological study and TCSS were significantly different in the three vitamin D groups. Regression analysis test demonstrated that 25 (OH) D level with 0.845 odds ratio is the only risk factor for the development of DSP. The serum levels of 25(OH)D below 15 ng/mL is associated with DSP. Conclusion: This study indicate that vitamin D deficiency is a risk factor for the development of DSP, and serum 25(OH)D level ≤ 15 ng/ml is crucial in assessing the severity of neuropathic symptoms.
URI: https://doi.org/10.5455/annalsmedres.2021.12.659
https://search.trdizin.gov.tr/yayin/detay/1119440
https://hdl.handle.net/11499/50725
ISSN: 2636-7688
Appears in Collections:Tıp Fakültesi Koleksiyonu
TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection

Files in This Item:
File SizeFormat 
document - 2024-03-18T105219.904.pdf2.1 MBAdobe PDFView/Open
Show full item record



CORE Recommender

Page view(s)

64
checked on Aug 24, 2024

Download(s)

12
checked on Aug 24, 2024

Google ScholarTM

Check




Altmetric


Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.