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https://hdl.handle.net/11499/50733
Title: | Removal of amoxicillin via chromatographic monolithic columns: comparison between batch and continuous fixed bed | Authors: | Ağlamaz, Mustafa Deniz Şarkaya, Koray Türkmen, Deniz Uçar, Mustafa Denizli, Adil |
Keywords: | Monolithic column hydrophobic interaction liquid chromatography amoxicillin adsorption |
Abstract: | This study preŞented a hydrophobic interaction-based poly(HEMA-MATrp) monolithic chromatographic column (MCC) to remove amoxicillin from aqueous solutions. In addition to their porous structure, monolithic-filled columns offer superior properties without loss of performance, which is one of the points that make them unique. The specific surface area of the monolithic column synthesized by the bulk polymerization of 2-hydroxyethyl methacrylate and N-Methacryloyl-L-tryptophan. Also, poly(HEMA- MATrp) MCC has been characterized via FTIR, SEM, and elemental analysis. According to BET analysis, the specific surface area of the poly(HEMA-MATrp) monolithic chromatographic column (MCC) is 14.2 mg/g. The adsorption and desorption of amoxicillin in an aqueous solution were investigated comparatively in both continuous fixed bed and batch adsorption. The highest adsorption value of amoxicillin was determined at pH 7 in the preŞence of PBS as 62.11 mg/g. The appropriate adsorption isotherm for the adsorption of amoxicillin was Langmuir, and the reaction kinetics was pseudo-second-order. No significant loss was observed for the adsorption capacity of poly(HEMA-MATrp) MCC after the 5 cycles of adsorption-desorption studies. Also, the loss for the adsorption capacity of the monolithic column is just %5.2 after 6-month storage, proving the reusability and storability of the monolithic column. | URI: | https://doi.org/10.55730/1300-0527.3520 https://search.trdizin.gov.tr/yayin/detay/1158660 https://hdl.handle.net/11499/50733 |
ISSN: | 1300-0527 1303-6130 |
Appears in Collections: | Fen-Edebiyat Fakültesi Koleksiyonu Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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Removal of amoxicillin via chromatographic monolithic columns_ co.pdf | 1.13 MB | Adobe PDF | View/Open |
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