Anthelmintic Activities of Methanol Extracts of Five Different Geophyte Plant Species

Abstract

The purpose of this study was to look into the in vitro anthelmintic activities of methanol extracts of Hyacinthella lineata (Steud. ex Schult. & Schult.f.) Chouard, Ornithogalum umbellatum L., Allium reuterianum Boiss., Cyclamen coum Mill., and Sternbergia clusiana (Ker Gawl.) Ker Gawl. ex Spreng.. The paralysis and death times of the Indian earthworm, Cosmocerca ornata, were used to assess anthelmintic activity. Three different concentrations, (5,10 and 20 mg mL(-1)) of methanol extracts were used to determine the time required to paralyze and to induce death in the earthworms. Albendazole (15 mg mL(-1)) was used as reference standard drug. Plant extracts at higher concentrations (20 mg mL(-1)) produced faster paralytic effects and a shorter time to death. The results revealed that S. clusiana killed all of the test worms within 20 +/- 0.6 min of exposure and was 100% effective. Among all five plants extracts tested, S. clusiana was found to be highly effective and significant against C. ornata. The findings will aid in understanding the significance and application of these medicinal plant species in the food industry, traditional medicine, and pharmaceutical applications. This anthelmintic study of the plant extracts revealed that traditional medicine may be as effective as modern medicine in combating pathogenic microorganisms.