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https://hdl.handle.net/11499/51195
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DC Field | Value | Language |
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dc.contributor.author | Şimşek, F. Selçuk | - |
dc.contributor.author | Çakmak, Muharrem | - |
dc.contributor.author | Kuşlu, Duygu | - |
dc.contributor.author | Balcı, Tansel A. | - |
dc.contributor.author | İn, Erdal | - |
dc.contributor.author | Özercan, İbrahim H. | - |
dc.contributor.author | Narin, Yavuz | - |
dc.date.accessioned | 2023-06-13T19:12:44Z | - |
dc.date.available | 2023-06-13T19:12:44Z | - |
dc.date.issued | 2023 | - |
dc.identifier.issn | 1734-1922 | - |
dc.identifier.issn | 1896-9151 | - |
dc.identifier.uri | https://doi.org/10.5114/aoms/111529 | - |
dc.identifier.uri | https://hdl.handle.net/11499/51195 | - |
dc.description.abstract | Introduction: There is no consensus about the standardized uptake value maximum (SUVmax) cut-off value to characterize pleural thickening world-wide. Sometimes, this causes unnecessary invasive diagnostic procedures. Our first aim is to determine a cut-off value for SUVmax. Secondly, we try to answer the following question: If we use this cut-off value together with morphological parameters, can we differentiate benign thickening from ma-lignant pleural mesothelioma (MPM) more accurately? Materialand methods:Thirty-seven patientswho underwent 2-deoxy-2-fluoro-D-glucose ([18F]FDG) positron emission tomography/computed tomography (PET/CT) before pleural biopsy were included the study. All of patients had histopathologically proven primary pleural disease. Their [18F]FDG-PET/CT im-aging reports were re-assessed. If a patient's SUVmax or size of the thickening was not mentioned in the report, we calculated it with their [18F]FDG-PET/CT. Results: Age, pleural effusion, size, and SUVmax were found to have a relation-ship with MPM. We found the size > 14 mm, and SUVmax > 4.0 as cut-off values for MPM. The sensitivity, specificity, positive predictive value (PPV), and nega-tive predictive value (NPV) for size > 14 mm were found to be 86.4%, 85.2%, 82.6%, 88.5%, respectively. For SUVmax > 4.0, sensitivity, specificity, PPV, NPV were 90.9%, 87.0%, 85.1%, 92.2%, respectively. Conclusions: If a patient has SUVmax> 4.0 and/or size > 14 mm, the risk of MPM is high. These patients should undergo biopsy. If a patient's SUVmax < 4.0, size < 14 mm and does not have pleural effusion, he/she has low risk for MPM. These patients can undergo the follow-up. If a patient's SUVmax < 4, size < 14, and has pleural effusion the MPM risk is approximately 4%. These patients can undergo biopsy/cytology/follow-up. Novel studies are needed for these patients. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Termedia Publishing House Ltd | en_US |
dc.relation.ispartof | Archives of Medical Science | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | mesothelioma | en_US |
dc.subject | cut-off value | en_US |
dc.subject | pleural thickening | en_US |
dc.subject | 18F-FDG-PET | en_US |
dc.subject | Mesothelioma | en_US |
dc.subject | Diagnosis | en_US |
dc.title | How can we use positron emission tomography/ computed tomography more accurately for characterization of asbestos-related pleural thickening? | en_US |
dc.type | Article | en_US |
dc.identifier.volume | 19 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.startpage | 385 | en_US |
dc.identifier.endpage | 391 | en_US |
dc.department | Pamukkale University | en_US |
dc.identifier.doi | 10.5114/aoms/111529 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.authorscopusid | 56903959400 | - |
dc.authorscopusid | 35147662600 | - |
dc.authorscopusid | 56904287200 | - |
dc.authorscopusid | 8922657100 | - |
dc.authorscopusid | 21742842200 | - |
dc.authorscopusid | 7004374166 | - |
dc.authorscopusid | 6601970889 | - |
dc.identifier.pmid | 37034512 | en_US |
dc.identifier.scopus | 2-s2.0-85152245821 | en_US |
dc.identifier.wos | WOS:000980693500014 | en_US |
dc.institutionauthor | … | - |
dc.identifier.scopusquality | Q2 | - |
item.languageiso639-1 | en | - |
item.openairetype | Article | - |
item.grantfulltext | open | - |
item.cerifentitytype | Publications | - |
item.fulltext | With Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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pdf-111529-88402.pdf | 91.18 kB | Adobe PDF | View/Open |
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