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https://hdl.handle.net/11499/51421
Title: | Evaluation of risk factors and detection of metallo-beta-lactamase enzyme production in carbapenem-resistant Pseudomonas and Acinetobacter species | Authors: | Öztürk Deniz, Suna Seçil Baykam, Nurcan |
Abstract: | Purpose: To investigate the frequency of MBLs in Pseudomonas and Acinetobacter species with E-test, to determine the risk factors and to evaluate the demographic and clinical features of infected patients. Materials and methods: Imipenem or meropenem resistance of Pseudomonas and Acinetobacter isolated from several clinical samples with conventional methods were evaluated with imipenem EDTA E-test and the presence of Metallo-β-lactameses MBL was examined. Several isolates were screened for VIM-1, VIM-2, IMP-1, and IMP-2 with a PCR test. Results: Of 46 carbapenem resistant Acinetobacter isolates, 41 (89%), as well as of 19 carbapenem resistant Pseudomonas isolates, 5 (26%) had MBL positivity with imipenem-EDTA E-test. A history of Intensive Care Unit stay, mechanical ventilation and cephalosporin use were found to be significant risk factors with respect to MBL production. Conclusion: Detection of MBL production in Acinetobacter and Pseudomonas species especially in ICU patients is of prime importance to control infection rapidly and effectively, which contribute to prevention of outbreaks. | URI: | https://doi.org/10.31362/patd.1142048 https://search.trdizin.gov.tr/yayin/detay/1163649 https://hdl.handle.net/11499/51421 |
ISSN: | 1309-9833 1308-0865 |
Appears in Collections: | Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection |
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Evaluation of risk factors and detection.pdf | 893.92 kB | Adobe PDF | View/Open |
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