Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/51421
Title: Evaluation of risk factors and detection of metallo-beta-lactamase enzyme production in carbapenem-resistant Pseudomonas and Acinetobacter species
Authors: Öztürk Deniz, Suna Seçil
Baykam, Nurcan
Abstract: Purpose: To investigate the frequency of MBLs in Pseudomonas and Acinetobacter species with E-test, to determine the risk factors and to evaluate the demographic and clinical features of infected patients. Materials and methods: Imipenem or meropenem resistance of Pseudomonas and Acinetobacter isolated from several clinical samples with conventional methods were evaluated with imipenem EDTA E-test and the presence of Metallo-β-lactameses MBL was examined. Several isolates were screened for VIM-1, VIM-2, IMP-1, and IMP-2 with a PCR test. Results: Of 46 carbapenem resistant Acinetobacter isolates, 41 (89%), as well as of 19 carbapenem resistant Pseudomonas isolates, 5 (26%) had MBL positivity with imipenem-EDTA E-test. A history of Intensive Care Unit stay, mechanical ventilation and cephalosporin use were found to be significant risk factors with respect to MBL production. Conclusion: Detection of MBL production in Acinetobacter and Pseudomonas species especially in ICU patients is of prime importance to control infection rapidly and effectively, which contribute to prevention of outbreaks. 
URI: https://doi.org/10.31362/patd.1142048
https://search.trdizin.gov.tr/yayin/detay/1163649
https://hdl.handle.net/11499/51421
ISSN: 1309-9833
1308-0865
Appears in Collections:Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection

Files in This Item:
File SizeFormat 
Evaluation of risk factors and detection.pdf893.92 kBAdobe PDFView/Open
Show full item record



CORE Recommender

Page view(s)

80
checked on Aug 24, 2024

Download(s)

16
checked on Aug 24, 2024

Google ScholarTM

Check




Altmetric


Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.