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https://hdl.handle.net/11499/5149
Title: | Production by Escherichia coli isolates of siderophore and other virulence factors and their pathogenic role in a cutaneous infection model | Authors: | Demir, Melek Kaleli, İlknur |
Keywords: | Aerobactin Cutaneous infection model Enterobactin Escherichia coli Siderophore Virulence factors aerobactin enterochelin siderophore virulence factor animal experiment animal model animal tissue article bacterial growth bacterium isolate control group controlled study feces analysis human mouse nonhuman pathogenesis priority journal sampling skin infection statistical significance urinary tract infection |
Publisher: | Blackwell Publishing Ltd | Abstract: | Escherichia coli isolates from urinary tract infections (UTIs) (n = 124), extra-urinary sites (n = 37) and normal faecal samples (n = 51) were examined for the presence of virulence factors, including siderophores (aerobactin and enterobactin). The proportion of aerobactin producers was significantly higher in UTI (69.4%; p 0.001) and extra-urinary samples (70.3%; p 0.007) than in controls (41.2%), while the proportion of enterobactin producers was significantly lower in the UTI samples than in the controls (p 0.027). In a cutaneous infection model, aerobactin-positive E. coli showed more growth than non-aerobactin and non-enterobactin isolates, even when other virulence factors were identical. © 2004 Copyright by the European Society of Clinical Microbiology and Infectious Diseases. | URI: | https://hdl.handle.net/11499/5149 https://doi.org/10.1111/j.1469-0691.2004.01001.x |
ISSN: | 1198-743X |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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