Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/51981
Title: Evaluation of renal function and ambulatory blood pressure monitoring in children and adolescents: The role of birthweight
Authors: Karayel, Nergis
Sönmez, Ferah
Girişgen, İlknur
Ünsal, Alparslan
Yenisey, Çiğdem
Önde, Mete
Keywords: Children
cystatin-C
low birth weight
renal function tests
Publisher: Galenos Publishing House
Abstract: Objective: A marked relationship is known between low birth weight and reduced nephron number. In this study, it was aimed to investigate the effects of low birth weight on renal function and blood pressure in healthy children and adolescents. Methods: This study was carried out on 33 children (7 to 18 years) who were born with a birth weight under 2500 g. The control group was composed of 30 children born at term with a birth weight appropriate for gestational age. Urine microalbumin, N-Acetyl-?-D Glucosaminidase, sodium levels and blood urea nitrogen, creatinine, and cystatin-C levels were investigated in patients and the control group. The sizes of kidneys in both groups were examined by ultrasonography. Blood pressure was monitored for 24 hours as ambulatory blood pressure. Results: The study group had higher levels of blood cystatin-C, urinary sodium, and N-Acetyl-?D-Glucosaminidase than the control group. Kidney volumes were smaller in the study group than in the controls. Conclusion: In our study, we observed that some glomerular and tubular functions were affected in children with low birth weight and in children born preterm. These effects were not observed in children with mature small for gestational age. Considering that nephron formation is completed at the 37th week, gestational age (prematurity) was thought to affect glomerular maturation more than intrauterine growth retardation. Our findings did not demonstrate hypertension in children born with low birth weight in childhood. We suggest that low birth weight children should be followed carefully for renal functions and blood pressure. © 2023 The authors. Published by Aydın Pediatric Society.
URI: https://hdl.handle.net/11499/51981
https://doi.org/10.59213/TP.2023.30074
https://search.trdizin.gov.tr/yayin/detay/1188919
ISSN: 2792-0429
Appears in Collections:Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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