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https://hdl.handle.net/11499/52090
Title: | The effect of vitamin D3 deficiency on hematological indices in Isfahan patients | Authors: | Tabatabaei, Seyed Mahdi Kianinodeh, Fatemeh Alibakhshi, Atena Hormozi, Sahar Saadi, Somayeh Nikpayam, Omid |
Abstract: | Aim: Since suboptimal vitamin D3 levels may be associated with anemia and several disorders, the study presented here investigated hematological indices state at patients with vitamin D3 deficiency. Methods: This cross-sectional study performed in Isfahan, Iran between 2017 and 2019. Initially, patient vitamin D3 level was determined. Based on vitamin D3 reference ranges them were divided into two vitamin D3-deficient (vitamin D3<25ng/mL) and control groups (>25ng/mL). Completed blood count was measured by hematology analyzer. Alkaline phosphatase (ALK) level was also measured and the results were statistically analyzed. Results: Of 1925 studied patients, 621 (32.3%) patients were male and 1274 (67.7%) females. 909 patients have an abnormal levels of vitamin D3 (<25ng/mL) and 1016 patients have sufficient vitamin D3 level. A weak correlation observed between white cell count and mean cell volume and low level of vitamin D3 (beta = 0.11). We also found a significant difference in mean age of patients with vitamin D3-deficient compared to control (p = 0.003). Moreover, we found no significant change in serum ALK levels between patients with vitamin D3 deficiency and control as well as subgroups of vitamin D3 deficiency. Conclusions: Vitamin D3 deficiency may not have significant impact on red cell count and indices, differential white blood cell count, and platelet count. It is suggested that a prospective cohort study be conducted in the future. | URI: | https://hdl.handle.net/11499/52090 https://doi.org/10.30714/j-ebr.2023.189 https://search.trdizin.gov.tr/yayin/detay/1188065 |
ISSN: | 2618-6454 |
Appears in Collections: | Mühendislik Fakültesi Koleksiyonu TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection |
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