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https://hdl.handle.net/11499/5224
Title: | Reperfusion injury after detorsion of unilateral ovarian torsion in rabbits | Authors: | Kaleli, Babür Aktan, E. Gezer, S. Kirkali, G. |
Keywords: | Adnexal torsion Free radicals Reperfusion injury thiobarbituric acid reactive substance analysis of variance animal experiment animal model animal tissue article controlled study female nonhuman ovariectomy ovary disease ovary torsion rabbit reperfusion injury statistical significance tissue level |
Publisher: | Elsevier Ireland Ltd | Abstract: | Objective: To determine if reperfusion injury takes place in ovarian tissue following the detorsion of the torsioned ovary. Study design: Fifty-four New Zealand mature nonpregnant female rabbits were divided into six groups. One group served to determine the basal values of thiobarbituric acid reacting substance (TBARS) and another group was sham. In the third and fourth groups, ovarian torsions and subsequent oophorectomy were performed in 1 and 3h, respectively. In the fifth and sixth groups, detorsions were carried out after unilateral ovarian torsion lasting 1 and 3h, respectively, then oophorectomies of the detorsioned ovaries were performed 2h after detorsion. The level of TBARS in ovarian tissues was determined in all subjects. Statistical analysis was performed using analysis of variance and Duncan's multiple range test. Differences were considered to be significant if P<0.05. Results: The levels of TBARS were not different in the basal and sham groups (P>0.05), while ovarian torsion caused significant increase in TBARS in the ovary (P<0.05), and detorsion caused a further significant increase in ovarian TBARS (P<0.05). Conclusion: Reperfusion injury in ovarian tissue, following the detorsion after the torsion of the ovary lasting up to 3h was demonstrated biochemically in this study. © 2003 Elsevier Science Ireland Ltd. All rights reserved. | URI: | https://hdl.handle.net/11499/5224 https://doi.org/10.1016/S0301-2115(03)00116-7 |
ISSN: | 0301-2115 |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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