Please use this identifier to cite or link to this item:
https://hdl.handle.net/11499/5265
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Limoncu, M.H. | - |
dc.contributor.author | Ermertcan, S. | - |
dc.contributor.author | Çetin, Çiğdem Banu | - |
dc.contributor.author | Cosar, G. | - |
dc.contributor.author | Dinç, G. | - |
dc.date.accessioned | 2019-08-16T11:43:54Z | |
dc.date.available | 2019-08-16T11:43:54Z | |
dc.date.issued | 2003 | - |
dc.identifier.issn | 0924-8579 | - |
dc.identifier.uri | https://hdl.handle.net/11499/5265 | - |
dc.identifier.uri | https://doi.org/10.1016/S0924-8579(03)00006-2 | - |
dc.description.abstract | The emergence of phenotypic resistance to ciprofloxacin and levofloxacin in methicillin-sensitive and methicillin-resistant Staphylococcus aureus (MRSA) strains was studied. Twenty MRSA and 77 methicillin-sensitive S.aureus (MSSA) strains susceptible to both quinolones were investigated for resistance after single step or serial passages. No growth of 20 MRSA strains was observed at 4×MIC of levofloxacin after 48 h incubation, but 4 of 77 (5%) MSSA strains grew at the same concentration. At 4×MIC concentration of ciprofloxacin, 10 MSSA (13%) and five MRSA (25%) strains were grown. In the serial passages of MRSA strains, resistance to ciprofloxacin was 75 and 5% for levofloxacin by the third passage. In the seventh passage this resistance was 100 and 15%, respectively. In MSSA strains, resistance to ciprofloxacin was 75 and 19% to levofloxacin at the third passage and at the seventh passage, 100 and 61%, respectively. Emergence of ciprofloxacin resistance was more common and developed more rapidly than resistance to levofloxacin in both MRSA and MSSA strains. © 2003 Elsevier Science B.V. and the International Society of Chemotherapy. All rights reserved. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Elsevier | en_US |
dc.relation.ispartof | International Journal of Antimicrobial Agents | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Ciprofloxacin | en_US |
dc.subject | Levofloxacin | en_US |
dc.subject | Phenotypic resistance | en_US |
dc.subject | Staphylococcus aureus | en_US |
dc.subject | ciprofloxacin | en_US |
dc.subject | levofloxacin | en_US |
dc.subject | quinoline derived antiinfective agent | en_US |
dc.subject | antibiotic resistance | en_US |
dc.subject | antibiotic sensitivity | en_US |
dc.subject | article | en_US |
dc.subject | bacterial growth | en_US |
dc.subject | bacterial strain | en_US |
dc.subject | bacterium culture | en_US |
dc.subject | concentration response | en_US |
dc.subject | controlled study | en_US |
dc.subject | incubation time | en_US |
dc.subject | methicillin resistant Staphylococcus aureus | en_US |
dc.subject | minimum inhibitory concentration | en_US |
dc.subject | nonhuman | en_US |
dc.subject | phenotype | en_US |
dc.subject | priority journal | en_US |
dc.title | Emergence of phenotypic resistance to ciprofloxacin and levofloxacin in methicillin-resistant and methicillin-sensitive Staphylococcus aureus strains | en_US |
dc.type | Article | en_US |
dc.identifier.volume | 21 | en_US |
dc.identifier.issue | 5 | en_US |
dc.identifier.startpage | 420 | |
dc.identifier.startpage | 420 | en_US |
dc.identifier.endpage | 424 | en_US |
dc.identifier.doi | 10.1016/S0924-8579(03)00006-2 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.pmid | 12727074 | en_US |
dc.identifier.scopus | 2-s2.0-0037404737 | en_US |
dc.identifier.wos | WOS:000183033400005 | en_US |
dc.identifier.scopusquality | Q1 | - |
dc.owner | Pamukkale_University | - |
item.languageiso639-1 | en | - |
item.openairetype | Article | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.fulltext | No Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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