Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/5398
Title: The use of amniotic membrane in flexor tendon repair: An experimental model
Authors: Demirkan, Fahir
Colakoglu, Nagehan
Herek, Özkan
Erkula, Gürkan
Keywords: Adhesion
Amniotic membrane
Flexor tendon
Reconstruction
Repair
adhesion
amnion
animal experiment
animal model
animal tissue
article
bioprosthesis
chicken
controlled study
cost effectiveness analysis
flexor muscle
flexor tendon injury
histology
nonhuman
postoperative complication
priority journal
tendon reconstruction
tendon sheath
tissue preparation
Publisher: Springer Verlag
Abstract: Background: The objective of this study was to investigate the use of amniotic membrane as a long-term bioprosthesis in hand surgery. The role of the amniotic membrane was investigated in chickens with regard to the prevention of adhesion formation following tendon repair in zone II. Methods: In the control group, the flexor tendon sheath was excised and the tendon repaired. In group II, both the flexor digitorum profundus tendon and its sheath were repaired. In group III, the repaired tendon was covered with amniotic membrane. Histological evaluation of the repaired tendons were done at 3, 6 and 12 weeks. Results: Results of histologic examination demonstrated that use of the amniotic membrane significantly reduced the amount of adhesion compared with the other groups. Three months after implantation no remnants of amniotic membrane could be identified at the tendon repair site. Conclusions: Amniotic membrane is easily prepared, and because of its cost effectiveness, its use in the prevention and treatment of adhesions should always be kept in mind.
URI: https://hdl.handle.net/11499/5398
https://doi.org/10.1007/s00402-002-0418-3
ISSN: 0936-8051
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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