Perioperative management of blood pressure in living donor kidney transplantation

Abstract

Purpose: Delayed graft function (DGF) is a poor clinical prognostic factor in kidney transplantation (KT) which frequently occurs due to acute kidney injury (AKI) within the postoperative first week. In the present study, we researched the effect of SBP (Systolic Blood Pressure) on early graft function after reperfusion in living-donor kidney transplantation. Materials and methods: We retrospectively obtained preoperative patient clinical data from anesthesia follow-up forms. The research data included demographic data, laboratory data, medical past and kidney-related information. SBP, central venous pressure [CVP], anesthesia duration, infusion and transfusion volumes, blood loss and urine output, surgery duration, ischemia duration and onset of graft diuresis were used as intraoperative data. Results: There was no significant difference between 4 different systolic blood pressure categories assigned after reperfusion of the kidney in terms of the related characteristics of the recipients. There were significant differences between the 4 groups categorized according to SBP after reperfusion in terms of the related in with intraoperative anesthetic and surgucal variable (p<.001). Conclusion: Systolic blood pressure over 140 mm Hg after reperfusion may be a safe level regarding long-term graft survival and mortality. It is needed to research the long-term prognosis of living donor kidney transplantation in larger study population to confirm the outcomes of our study. © 2023, Pamukkale University. All rights reserved.