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https://hdl.handle.net/11499/54955
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DC Field | Value | Language |
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dc.contributor.author | Karakok, Taliha | - |
dc.contributor.author | Gözükara, Melih Gaffar | - |
dc.contributor.author | Uygun Kızmaz, Yeşim | - |
dc.contributor.author | Demir, Yakup | - |
dc.contributor.author | Toruyenler Coşkunpınar, Melike | - |
dc.contributor.author | Altun Demircan, Şerife | - |
dc.contributor.author | Arslan, Yusuf | - |
dc.contributor.author | İlkören, Pelin | - |
dc.contributor.author | Alp Göker, Eda | - |
dc.contributor.author | Doğan, Ahmet | - |
dc.contributor.author | Tüzün, Türkan | - |
dc.contributor.author | Sevim, Şükran | - |
dc.contributor.author | Çakır, Yasemin | - |
dc.contributor.author | Işık, Mehmet Emirhan | - |
dc.contributor.author | Mermutoğlu, Çiğdem | - |
dc.contributor.author | Azap, Alpay | - |
dc.contributor.author | Kınıklı, Sami | - |
dc.contributor.author | Tekin, Süda | - |
dc.contributor.author | Şimşek Yavuz, Serap | - |
dc.contributor.author | Öner, Sedef Zeliha | - |
dc.date.accessioned | 2023-11-18T09:57:43Z | - |
dc.date.available | 2023-11-18T09:57:43Z | - |
dc.date.issued | 2023 | - |
dc.identifier.issn | 1300-932X | - |
dc.identifier.issn | 2602-2842 | - |
dc.identifier.uri | https://doi.org/10.5578/flora.20239716 | - |
dc.identifier.uri | https://hdl.handle.net/11499/54955 | - |
dc.description.abstract | Introduction: The objective of this study was to compare the risk factors and mortality rates of candidemia among patients with and without COVID-19 in the intensive care units (ICU).Materials and Methods: This study is a retrospective multicenter observational study, in ICUs of 12 hospitals (eight tertiary and four secondary hospitals) in Tarkiye. All adult patients (>18 years) hospitalized in ICUs and developed candidemia between 01.01.2020-31.12.2021 were included. The following data were collected: age, gender, nasopharyngeal swab SARS-CoV-2 PCR test, species of Candida (Candida albicans or non-albicans Candida), comorbidities, ICU stay, antibiotic use, corticosteroid, and anti-cytokine therapy, central venous catheter (CVC), abdominal surgery, parenteral nutrition, mechanical ventilation (MV), other cultures isolated Candida spp., echocardiography (ECO), mortality. Data from patients with or without COVID-19 were compared.Results: A total of 188 patients, 66 COVID-19 and 122 non-COVID-19, were included in the study. The median age of the patients was 69.5 and there were no differences between the groups. 185 (98.4%) patients had a history of antibiotic use. Sixteen patients, all from the COVID-19 group, had a history of anti-cytokine therapy. Corticosteroid use was higher in COVID-19 patients (p< 0.001). Intraabdominal surgery was higher in the non-COVID-19 group (p< 0.014). C. albicans was isolated from 36.7% of total patients and the remaining were non-albicans Candida species. The overall mortality was higher in COVID-19 patients (p= 0.014). Alzheimer's and malignancies were higher in non-COVID-19 patients. Intraabdominal surgery, MV, and CVC were higher in tertiary care hospitals whereas parenteral nutrition was higher in secondary care hospitals.Conclusion: Immunosuppressive treatments administered to COVID-19 patients pose a risk in terms of candidemia. Risk factors may differ between secondary and tertiary care hospitals. Preventable risk factors should be determined on a hospital basis and appropriate infection control measures should be taken. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Bilimsel Tip Yayinevi | en_US |
dc.relation.ispartof | Flora Infeksiyon Hastaliklari Ve Klinik Mikrobiyoloji Dergisi | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Candidemia | en_US |
dc.subject | COVID-19 | en_US |
dc.subject | Risk factors | en_US |
dc.subject | Intensive care unit | en_US |
dc.title | Analysis of Risk Factors Associated with Candidemia Among Patients with or without COVID-19 in Intensive Care Units During the Pandemic Process: A Multicenter Study | en_US |
dc.type | Article | en_US |
dc.identifier.volume | 28 | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.startpage | 456 | en_US |
dc.identifier.endpage | 465 | en_US |
dc.department | Pamukkale University | en_US |
dc.identifier.doi | 10.5578/flora.20239716 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.wos | WOS:001085015100013 | en_US |
dc.institutionauthor | … | - |
item.languageiso639-1 | en | - |
item.openairetype | Article | - |
item.grantfulltext | open | - |
item.cerifentitytype | Publications | - |
item.fulltext | With Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.03. Basic Medical Sciences | - |
Appears in Collections: | Tıp Fakültesi Koleksiyonu TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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document (96).pdf | 281.3 kB | Adobe PDF | View/Open |
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