Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/5514
Title: Magnetic resonance imaging with rectal Gd-DTPA: New tool for the diagnosis of perianal fistula
Authors: Sabir, Nuran
Sungurtekin, Uğur
Erdem, Ergün
Nessar, Mehmet
Keywords: Magnetic resonance imaging
Perianal fistula
Rectal Gd-DTPA administration
contrast medium
gadolinium pentetate
mannitol
adult
anus fistula
anus surgery
article
clinical article
clinical trial
controlled clinical trial
controlled study
diagnostic accuracy
diagnostic procedure
disease severity
enteritis
female
human
image analysis
male
medical assessment
nuclear magnetic resonance imaging
pathological anatomy
priority journal
recurrent disease
surgical technique
Adult
Contrast Media
Female
Gadolinium DTPA
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Rectal Fistula
Rectum
Abstract: This study investigated the effectiveness of magnetic resonance imaging (MRI) with rectal administration of the enteral contrast agent gadolinium diethylene triamine pentaacetic acid (Gd-DTPA) in the diagnosis of recurrent perianal fistulae, assessing the number, anatomical extent, location, and signal intensities of various lesions. Fistulas were examined by MRI before and after rectal administration of Gd-DTPA in 50 patients (excluding fistulas due to inflammatory bowel disease). Surgical findings were compared with both pre- and postcontrast T1-weighted, T2-weighted, and short T1 inversion recovery (STIR) sequences. Of the 68 fistulous tracts detected surgically, precontrast imaging identified 16 by T1-weighted images (hypointense), 27 by T2-weighted images (hyperintense or iso- to weakly hyperintense), and 54 by STIR. Postcontrast imaging identified 29 by T1-weighted images, 58 by T2-weighted, and 54 by STIR. MRI with rectal administration of Gd-DTPA thus facilitates determination of fistula tracts, which are better resolved by precontrast STIR than by either precontrast T1- or T2-weighted images. Postcontrast T2-weighted images were substantially superior to T1-weighted. Both non-contrast STIR and postcontrast T2-weighted sequences were adequate for classifying fistulas in ano, but in complex recurrent anal fistula post-contrast T2-weighted images were more helpful.
URI: https://hdl.handle.net/11499/5514
https://doi.org/10.1007/s003840000251
ISSN: 0179-1958
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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