Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/5565
Title: A practical analytical quality report on the effect of carotenemia on neonatal bilirubin levels
Authors: Aslan, Diler
Kuralay, F.
Tanyalcin, T.
Tanyalcin, O.
Keywords: Analytical interference
Analytical quality
Analytical quality indicator
Publisher: Springer New York
Abstract: The effect of haematocrit and ß-carotene levels on the serum total bilirubin measurement in two analytical methods was studied as an example of the impact of practical analytical quality in medical decision making. The precision characteristics of the two methods were very similar. Based upon the significant difference in the correlation coefficient in a method comparison study before and after 20% trimming of the data, an interference effect study was performed. Haemoglobin (expressed as haematocrit) and ß-carotene were the substances studied to explain the observed differences. The bilirubin test results from the Wako bilirubinometer were easily affected (n = 19; X(S): 13.83±2.43; t = -6.17; P = 0.000) and more elevated than in the Vitros dry chemistry systems (n = 18; X(S): 12.72±2.21; t = -2.48; P = 0.017), due to the presence of ß-carotene (>200 µg/dl).
URI: https://hdl.handle.net/11499/5565
https://doi.org/10.1007/s007690050011
ISSN: 0949-1775
Appears in Collections:Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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