Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/56059
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dc.contributor.authorŞimşek, S.-
dc.contributor.authorEr, Urgancı, B.-
dc.contributor.authorYılmaz, S.-
dc.contributor.authorAykota, M.R.-
dc.contributor.authorSarı, T.-
dc.contributor.authorAçıkbaş, I.-
dc.date.accessioned2023-12-16T06:44:47Z-
dc.date.available2023-12-16T06:44:47Z-
dc.date.issued2023-
dc.identifier.issn2284-0729-
dc.identifier.urihttp://dx.doi.org/10.26355/eurrev_202311_34340-
dc.identifier.urihttps://hdl.handle.net/11499/56059-
dc.description.abstractOBJECTIVE: Obesity is a major risk factor for developing a number of serious diseases, such as cardiometabolic changes and cancer. An increase in adipose tissue and a decrease in antioxidant capacity both contribute to the etiopathogenesis of these comorbidities. The most effective method in the treatment of morbid obesity is bariatric surgery. Laparoscopic sleeve gastrectomy (LSG) is the most preferred method in bariatric surgery today. In this study, the potential improvement effect of laparoscopic sleeve gastrectomy (LSG) surgery in the restoration of weight loss and endocrine and tissue-based deterioration was obtained by evaluating changes in oxidative stress, antioxidant agents, and lipid oxidation levels. PATIENTS AND METHODS: Fifty patients who had LSG surgery were chosen, along with 50 healthy volunteers who were the same age and gender as these patients. Serum total antioxidant capacity measurement, total oxidant capacity measurement, malondialdehyde (MDA) for the measurement of lipid peroxidation degree, and superoxide dismutase (SOD) and glutathione peroxidase (GPx) levels for the measurement of antioxidant levels were measured colorimetrically with the help of a commercial kit. RESULTS: Oxidative stress indices, MDA levels, and GPx levels of patients with morbid obesity treated with LSG were observed to decrease significantly compared to the preoperative period, while no significant changes were observed in SOD levels. CONCLUSIONS: In patients with morbidly obese conditions, the weight control achieved by sleeve gastrectomy, which is a restrictive method and thus causes a decrease in adipose tissue, causes a decrease in oxidative stress and an increase in the antioxidant response.en_US
dc.language.isoenen_US
dc.relation.ispartofEuropean review for medical and pharmacological sciencesen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectantioxidanten_US
dc.subjectsuperoxide dismutaseen_US
dc.subjectfollow upen_US
dc.subjectgastrectomyen_US
dc.subjecthumanen_US
dc.subjectlaparoscopyen_US
dc.subjectmorbid obesityen_US
dc.subjectoxidative stressen_US
dc.subjectproceduresen_US
dc.subjecttreatment outcomeen_US
dc.subjectAntioxidantsen_US
dc.subjectFollow-Up Studiesen_US
dc.subjectGastrectomyen_US
dc.subjectHumansen_US
dc.subjectLaparoscopyen_US
dc.subjectObesity, Morbiden_US
dc.subjectOxidative Stressen_US
dc.subjectSuperoxide Dismutaseen_US
dc.subjectTreatment Outcomeen_US
dc.titleOne-year follow-up of the oxidative stress profile of patients after laparoscopic sleeve gastrectomyen_US
dc.typeArticleen_US
dc.identifier.volume27en_US
dc.identifier.issue21en_US
dc.identifier.startpage10605en_US
dc.identifier.endpage10611en_US
dc.departmentPamukkale Universityen_US
dc.identifier.doi10.26355/eurrev_202311_34340-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.authorscopusid49862095700-
dc.authorscopusid58703632600-
dc.authorscopusid57216092088-
dc.authorscopusid57195457964-
dc.authorscopusid36519596600-
dc.authorscopusid6507893937-
dc.identifier.pmid37975385en_US
dc.identifier.scopus2-s2.0-85177479860en_US
dc.institutionauthor-
item.languageiso639-1en-
item.grantfulltextnone-
item.fulltextNo Fulltext-
item.cerifentitytypePublications-
item.openairetypeArticle-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
crisitem.author.dept14.03. Basic Medical Sciences-
crisitem.author.dept14.03. Basic Medical Sciences-
crisitem.author.dept14.01. Surgical Medicine-
crisitem.author.dept14.01. Surgical Medicine-
crisitem.author.dept14.02. Internal Medicine-
crisitem.author.dept14.03. Basic Medical Sciences-
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
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