Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/5611
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dc.contributor.authorSuzer, T.-
dc.contributor.authorTahta, K.-
dc.contributor.authorCelik, H.-
dc.contributor.authorOzcan, O.E.-
dc.date.accessioned2019-08-16T11:50:34Z-
dc.date.available2019-08-16T11:50:34Z-
dc.date.issued1999-
dc.identifier.issn1019-5149-
dc.identifier.urihttps://hdl.handle.net/11499/5611-
dc.description.abstractThe purpose of this study was to investigate the preventive effect of Ticlopidine on thrombus formation after surgical arterial injury. The model of microsurgical carotid endarterectomy was performed on the common carotid arteries in rats. Twenty rats were equally divided into two groups: a control group that received no drugs and a Ticlopidine-treated group (100mg/kg orally 3 hours before surgery). The vessels were prepared for scanning electron microscopy and were evaluated based on the platelet aggregates at the endarterectomized site. The Mann-Whitney U test identified a statistically significant difference between the control group and the drug-treated group (U=82.50, p< 0.05). This study proves that Ticlopidine has a preventive effect on platelet aggregation in endarterectomized carotid arteries and that it can be used to reduce postoperative thrombus formation after carotid endarterectomy.en_US
dc.language.isoenen_US
dc.publisherTurkish Neurosurgical Societyen_US
dc.relation.ispartofTurkish Neurosurgeryen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCarotid endarterectomyen_US
dc.subjectMicroneurosurgeryen_US
dc.subjectPostoperative thrombosisen_US
dc.subjectScanning electron microscopyen_US
dc.subjectThrombus formationen_US
dc.subjectTiclopidineen_US
dc.subjectticlopidineen_US
dc.subjectanimal experimenten_US
dc.subjectanimal modelen_US
dc.subjectanimal tissueen_US
dc.subjectaorta injuryen_US
dc.subjectarticleen_US
dc.subjectcarotid endarterectomyen_US
dc.subjectcontrolled studyen_US
dc.subjectmicrosurgeryen_US
dc.subjectnonhumanen_US
dc.subjectoral drug administrationen_US
dc.subjectpostoperative complicationen_US
dc.subjectraten_US
dc.subjectscanning electron microscopyen_US
dc.subjectthrombocyte aggregationen_US
dc.subjectthrombosisen_US
dc.titlePreventive effect of ticlopidine on postoperative thrombus formation after experimental microsurgical carotid endarterectomy in ratsen_US
dc.typeArticleen_US
dc.identifier.volume9en_US
dc.identifier.issue1-2en_US
dc.identifier.startpage59
dc.identifier.startpage59en_US
dc.identifier.endpage63en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.scopus2-s2.0-0032719253en_US
dc.identifier.scopusqualityQ4-
dc.ownerPamukkale_University-
item.openairetypeArticle-
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.cerifentitytypePublications-
Appears in Collections:Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
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