Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/5626
Title: Use of averages of patient data for quality control [Article]
Authors: Aslan, Diler
Kuralay, Filiz
Tanyalsin, T.
Topraksu, M.
Keywords: Control limits
Daily quality control
Patients' data statistics
Truncation limits
Publisher: Springer New York
Abstract: Applicability of Hoffman's average of normals (AON) method was evaluated in quality control (QC) for twenty clinical chemistry assays (ALT, Alb, ALP, AMY, AST, T. Bil, inP, Glu, Ca, Cl, T. Chol, Creat, CK, K, LD, T. Prot., Na, TG, BUN, Uric. A.) performed routinely in the Hospital of Medical Faculty of 9 Eylül University. Consecutive Texas Instruments XL-Dacos patient data were accumulated over 10 days. According to the guidelines developed by Cembrowsky et. al. for the implementation of average of patients (AOP) (also known as AON) procedure, the patient population mean, X¯p, population standard deviation, Sp, the ratio of Sp/Sa (Sa, the analytical standard deviation), and the approximate number of patient results averaged. Np (with Ped = 0.50) were determined from the nomogram constructed by Cembrowsky et. al., illustrating the relationship between Np, Sp/Sa, and the probability of detecting a 2Sa shift (Ped) when the probability of false rejection, Pfr, is 0.01. The control limits and the truncation limits were selected as X¯p±2Sp and X¯p±2.58×Sp?Np, respectively. The estimated values were assessed for the applicability of AOP procedures in the clinical laboratory. We conclude that the AOP procedure is a valuable tool for instrument monitoring as an adjunct to more costly standard QC procedures and is also an efficient, cost-effective and rapid way of collecting appropriate information on large number of patients.
URI: https://hdl.handle.net/11499/5626
https://doi.org/10.1007/s007690050403
ISSN: 0949-1775
Appears in Collections:Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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