Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/56265
Full metadata record
DC FieldValueLanguage
dc.contributor.authorKaymaz, Serdar-
dc.contributor.authorKavas, Murat-
dc.contributor.authorDemiray, Aydın-
dc.contributor.authorKarasu, Uğur-
dc.contributor.authorÇobankara, Veli-
dc.contributor.authorBoğa, Sibel-
dc.date.accessioned2024-01-21T19:50:24Z-
dc.date.available2024-01-21T19:50:24Z-
dc.date.issued2023-
dc.identifier.issn2618-6500-
dc.identifier.urihttps://doi.org/10.46497/ArchRheumatol.2022.9239-
dc.identifier.urihttps://hdl.handle.net/11499/56265-
dc.description.abstractObjectives: This study aims to investigate the relationship between the interferon-gamma receptor 1 (IFNGR1) polymorphism and susceptibility to lung sarcoidosis. Patients and methods: The study included a total of 55 patients (13 males, 42 females; mean age: 46.5 +/- 9.1 years; range, 22 to 66 years) with lung sarcoidosis and 28 healthy controls (6 males, 22 females; mean age: 43.9 +/- 5.9 years; range 22 to 60 years) selected from the Turkish population. The polymerase chain reaction was used for genotyping of participants to determine single-nucleotide polymorphisms. Hardy- Weinberg equilibrium, which is considered an important tool for detecting genotyping errors, was tested. Allele and genotype frequencies of patients and controls were compared using logistic regression analysis. Results: The analyses showed no correlation between the tested IFNGR1 single-nucleotide polymorphism (rs2234711) and lung sarcoidosis (p>0.05). The categorization analysis according to the clinical features, laboratory, and radiographic characteristics showed no correlation between the tested polymorphism of IFNGR1 (rs2234711) and these characteristics (p>0.05). Conclusion: The results of the study showed that the tested gene polymorphism (rs2234711) of IFNGR1 was not associated with lung sarcoidosis. More comprehensive studies are needed to verify our results.en_US
dc.language.isoenen_US
dc.publisherTurkish League Against Rheumatismen_US
dc.relation.ispartofArchives of Rheumatologyen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectInterferon-gamma receptor 1en_US
dc.subjectsarcoidosisen_US
dc.subjectpolymorphism.en_US
dc.subjectPulmonary Sarcoidosisen_US
dc.subjectTh17 Cellsen_US
dc.subjectIfn-Gammaen_US
dc.subjectRisken_US
dc.subjectAssociationen_US
dc.subjectInfectionen_US
dc.subjectCytokinesen_US
dc.subjectPromoteren_US
dc.subjectLymphocytesen_US
dc.subjectTherapyen_US
dc.titleInvestigation of the relationship between interferon-gamma receptor 1-56C/ T gene polymorphism and genetic susceptibility to lung sarcoidosis: A cross-sectional study [2]en_US
dc.typeArticleen_US
dc.identifier.volume38en_US
dc.identifier.issue1en_US
dc.identifier.startpage1en_US
dc.identifier.endpage8en_US
dc.departmentPamukkale Universityen_US
dc.authoridDemiray, Aydın/0000-0002-3343-0184-
dc.authoridKAYMAZ, SERDAR/0000-0002-6958-5436-
dc.identifier.doi10.46497/ArchRheumatol.2022.9239-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.authorwosidDemiray, Aydın/AEN-1780-2022-
dc.authorwosidKavas, Murat/HNT-0352-2023-
dc.identifier.pmid37235124en_US
dc.identifier.wosWOS:001101876400001en_US
dc.institutionauthor-
item.languageiso639-1en-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.openairetypeArticle-
item.grantfulltextnone-
crisitem.author.dept14.02. Internal Medicine-
crisitem.author.dept14.02. Internal Medicine-
crisitem.author.dept14.02. Internal Medicine-
crisitem.author.dept14.02. Internal Medicine-
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
Show simple item record



CORE Recommender

WEB OF SCIENCETM
Citations

1
checked on Nov 16, 2024

Page view(s)

50
checked on Aug 24, 2024

Google ScholarTM

Check




Altmetric


Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.