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https://hdl.handle.net/11499/56265
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kaymaz, Serdar | - |
dc.contributor.author | Kavas, Murat | - |
dc.contributor.author | Demiray, Aydın | - |
dc.contributor.author | Karasu, Uğur | - |
dc.contributor.author | Çobankara, Veli | - |
dc.contributor.author | Boğa, Sibel | - |
dc.date.accessioned | 2024-01-21T19:50:24Z | - |
dc.date.available | 2024-01-21T19:50:24Z | - |
dc.date.issued | 2023 | - |
dc.identifier.issn | 2618-6500 | - |
dc.identifier.uri | https://doi.org/10.46497/ArchRheumatol.2022.9239 | - |
dc.identifier.uri | https://hdl.handle.net/11499/56265 | - |
dc.description.abstract | Objectives: This study aims to investigate the relationship between the interferon-gamma receptor 1 (IFNGR1) polymorphism and susceptibility to lung sarcoidosis. Patients and methods: The study included a total of 55 patients (13 males, 42 females; mean age: 46.5 +/- 9.1 years; range, 22 to 66 years) with lung sarcoidosis and 28 healthy controls (6 males, 22 females; mean age: 43.9 +/- 5.9 years; range 22 to 60 years) selected from the Turkish population. The polymerase chain reaction was used for genotyping of participants to determine single-nucleotide polymorphisms. Hardy- Weinberg equilibrium, which is considered an important tool for detecting genotyping errors, was tested. Allele and genotype frequencies of patients and controls were compared using logistic regression analysis. Results: The analyses showed no correlation between the tested IFNGR1 single-nucleotide polymorphism (rs2234711) and lung sarcoidosis (p>0.05). The categorization analysis according to the clinical features, laboratory, and radiographic characteristics showed no correlation between the tested polymorphism of IFNGR1 (rs2234711) and these characteristics (p>0.05). Conclusion: The results of the study showed that the tested gene polymorphism (rs2234711) of IFNGR1 was not associated with lung sarcoidosis. More comprehensive studies are needed to verify our results. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Turkish League Against Rheumatism | en_US |
dc.relation.ispartof | Archives of Rheumatology | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Interferon-gamma receptor 1 | en_US |
dc.subject | sarcoidosis | en_US |
dc.subject | polymorphism. | en_US |
dc.subject | Pulmonary Sarcoidosis | en_US |
dc.subject | Th17 Cells | en_US |
dc.subject | Ifn-Gamma | en_US |
dc.subject | Risk | en_US |
dc.subject | Association | en_US |
dc.subject | Infection | en_US |
dc.subject | Cytokines | en_US |
dc.subject | Promoter | en_US |
dc.subject | Lymphocytes | en_US |
dc.subject | Therapy | en_US |
dc.title | Investigation of the relationship between interferon-gamma receptor 1-56C/ T gene polymorphism and genetic susceptibility to lung sarcoidosis: A cross-sectional study [2] | en_US |
dc.type | Article | en_US |
dc.identifier.volume | 38 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.startpage | 1 | en_US |
dc.identifier.endpage | 8 | en_US |
dc.department | Pamukkale University | en_US |
dc.authorid | Demiray, Aydın/0000-0002-3343-0184 | - |
dc.authorid | KAYMAZ, SERDAR/0000-0002-6958-5436 | - |
dc.identifier.doi | 10.46497/ArchRheumatol.2022.9239 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.authorwosid | Demiray, Aydın/AEN-1780-2022 | - |
dc.authorwosid | Kavas, Murat/HNT-0352-2023 | - |
dc.identifier.pmid | 37235124 | en_US |
dc.identifier.wos | WOS:001101876400001 | en_US |
dc.institutionauthor | … | - |
item.languageiso639-1 | en | - |
item.fulltext | No Fulltext | - |
item.openairetype | Article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | none | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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