Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/56265
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dc.contributor.authorKaymaz, Serdar-
dc.contributor.authorKavas, Murat-
dc.contributor.authorDemiray, Aydın-
dc.contributor.authorKarasu, Uğur-
dc.contributor.authorÇobankara, Veli-
dc.contributor.authorBoğa, Sibel-
dc.date.accessioned2024-01-21T19:50:24Z-
dc.date.available2024-01-21T19:50:24Z-
dc.date.issued2023-
dc.identifier.issn2618-6500-
dc.identifier.urihttps://doi.org/10.46497/ArchRheumatol.2022.9239-
dc.identifier.urihttps://hdl.handle.net/11499/56265-
dc.description.abstractObjectives: This study aims to investigate the relationship between the interferon-gamma receptor 1 (IFNGR1) polymorphism and susceptibility to lung sarcoidosis. Patients and methods: The study included a total of 55 patients (13 males, 42 females; mean age: 46.5 +/- 9.1 years; range, 22 to 66 years) with lung sarcoidosis and 28 healthy controls (6 males, 22 females; mean age: 43.9 +/- 5.9 years; range 22 to 60 years) selected from the Turkish population. The polymerase chain reaction was used for genotyping of participants to determine single-nucleotide polymorphisms. Hardy- Weinberg equilibrium, which is considered an important tool for detecting genotyping errors, was tested. Allele and genotype frequencies of patients and controls were compared using logistic regression analysis. Results: The analyses showed no correlation between the tested IFNGR1 single-nucleotide polymorphism (rs2234711) and lung sarcoidosis (p>0.05). The categorization analysis according to the clinical features, laboratory, and radiographic characteristics showed no correlation between the tested polymorphism of IFNGR1 (rs2234711) and these characteristics (p>0.05). Conclusion: The results of the study showed that the tested gene polymorphism (rs2234711) of IFNGR1 was not associated with lung sarcoidosis. More comprehensive studies are needed to verify our results.en_US
dc.language.isoenen_US
dc.publisherTurkish League Against Rheumatismen_US
dc.relation.ispartofArchives of Rheumatologyen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectInterferon-gamma receptor 1en_US
dc.subjectsarcoidosisen_US
dc.subjectpolymorphism.en_US
dc.subjectPulmonary Sarcoidosisen_US
dc.subjectTh17 Cellsen_US
dc.subjectIfn-Gammaen_US
dc.subjectRisken_US
dc.subjectAssociationen_US
dc.subjectInfectionen_US
dc.subjectCytokinesen_US
dc.subjectPromoteren_US
dc.subjectLymphocytesen_US
dc.subjectTherapyen_US
dc.titleInvestigation of the relationship between interferon-gamma receptor 1-56C/ T gene polymorphism and genetic susceptibility to lung sarcoidosis: A cross-sectional study [2]en_US
dc.typeArticleen_US
dc.identifier.volume38en_US
dc.identifier.issue1en_US
dc.identifier.startpage1en_US
dc.identifier.endpage8en_US
dc.departmentPamukkale Universityen_US
dc.authoridDemiray, Aydın/0000-0002-3343-0184-
dc.authoridKAYMAZ, SERDAR/0000-0002-6958-5436-
dc.identifier.doi10.46497/ArchRheumatol.2022.9239-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.authorwosidDemiray, Aydın/AEN-1780-2022-
dc.authorwosidKavas, Murat/HNT-0352-2023-
dc.identifier.pmid37235124en_US
dc.identifier.wosWOS:001101876400001en_US
dc.institutionauthor-
item.languageiso639-1en-
item.fulltextNo Fulltext-
item.openairetypeArticle-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.grantfulltextnone-
crisitem.author.dept14.02. Internal Medicine-
crisitem.author.dept14.02. Internal Medicine-
crisitem.author.dept14.02. Internal Medicine-
crisitem.author.dept14.02. Internal Medicine-
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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