Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/56298
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dc.contributor.authorSek, S. Sim-
dc.contributor.authorUrganci, B. Er-
dc.contributor.authorYilmaz, S.-
dc.contributor.authorAykota, M. R.-
dc.contributor.authorSari, T.-
dc.contributor.authorAcikbas, I.-
dc.date.accessioned2024-01-21T19:50:29Z-
dc.date.available2024-01-21T19:50:29Z-
dc.date.issued2023-
dc.identifier.issn1128-3602-
dc.identifier.urihttps://hdl.handle.net/11499/56298-
dc.description.abstract- OBJECTIVE: Obesity is a ma-jor risk factor for developing a number of seri-ous diseases, such as cardiometabolic chang-es and cancer. An increase in adipose tissue and a decrease in antioxidant capacity both con-tribute to the etiopathogenesis of these comor-bidities. The most effective method in the treat-ment of morbid obesity is bariatric surgery. Lap-aroscopic sleeve gastrectomy (LSG) is the most preferred method in bariatric surgery today. In this study, the potential improvement effect of laparoscopic sleeve gastrectomy (LSG) surgery in the restoration of weight loss and endocrine and tissue-based deterioration was obtained by evaluating changes in oxidative stress, antioxi-dant agents, and lipid oxidation levels. PATIENTS AND METHODS: Fifty patients who had LSG surgery were chosen, along with 50 healthy volunteers who were the same age and gender as these patients. Serum total antiox-idant capacity measurement, total oxidant capac-ity measurement, malondialdehyde (MDA) for the measurement of lipid peroxidation degree, and superoxide dismutase (SOD) and glutathione per-oxidase (GPx) levels for the measurement of an-tioxidant levels were measured colorimetrically with the help of a commercial kit. RESULTS: Oxidative stress indices, MDA lev-els, and GPx levels of patients with morbid obe-sity treated with LSG were observed to decrease significantly compared to the preoperative peri- od, while no significant changes were observed in SOD levels. CONCLUSIONS: In patients with morbidly obese conditions, the weight control achieved by sleeve gastrectomy, which is a restrictive method and thus causes a decrease in adipose tissue, causes a decrease in oxidative stress and an increase in the antioxidant response.en_US
dc.description.sponsorshipScientific Research Coordination Unit of Pamukkale University [2019BSP024]en_US
dc.description.sponsorshipThis study was supported by the Scientific Research Coordination Unit of Pamukkale University, under project No. 2019BSP024.en_US
dc.language.isoenen_US
dc.publisherVerduci Publisheren_US
dc.relation.ispartofEuropean Review For Medical and Pharmacological Sciencesen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLaparoscopic sleeve gastrectomyen_US
dc.subjectOxidative stressen_US
dc.subjectMDAen_US
dc.subjectSODen_US
dc.subjectGPxen_US
dc.subjectObesityen_US
dc.subjectAntioxidantsen_US
dc.subjectAccumulationen_US
dc.subjectMechanismsen_US
dc.subjectReductionen_US
dc.subjectDiseaseen_US
dc.subjectImpacten_US
dc.titleOne-year follow-up of the oxidative stress profile of patients after laparoscopic sleeve gastrectomyen_US
dc.typeArticleen_US
dc.identifier.volume27en_US
dc.identifier.issue21en_US
dc.identifier.startpage10605en_US
dc.identifier.endpage10611en_US
dc.departmentPamukkale Universityen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.pmid37975385en_US
dc.identifier.wosWOS:001110599700007en_US
dc.institutionauthor-
item.languageiso639-1en-
item.fulltextNo Fulltext-
item.openairetypeArticle-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.grantfulltextnone-
crisitem.author.dept14.03. Basic Medical Sciences-
crisitem.author.dept14.01. Surgical Medicine-
crisitem.author.dept14.03. Basic Medical Sciences-
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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