Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/5641
Title: Nonrelated living-donor kidney transplantation: Medical and ethical aspects
Authors: Çolakoglu, Murat
Yenicesu, Müjdat
Akpolat, Tekin
Vural, Abdülgaffar
Utaş, C.
Arinsoy, T.
Sindel, Ş.
Keywords: Kidney transplantation
Non-related living-donor kidneys
Organ trading
cyclosporin a
adolescent
adult
article
female
follow up
graft rejection
graft survival
human
india
infection
kidney transplantation
liver disease
living donor
major clinical study
male
medical ethics
mortality
nephrotoxicity
preoperative care
priority journal
survival rate
turkey (republic)
Empirical Approach
Health Care and Public Health
Adolescent
Adult
Cause of Death
Ethics, Medical
Female
Follow-Up Studies
Graft Survival
Humans
India
Kidney Failure, Chronic
Kidney Transplantation
Living Donors
Male
Middle Aged
Survival Analysis
Treatment Outcome
Turkey
Abstract: Several patients with end-stage renal disease went to Bombay for renal transplantation from nonrelated living donors and then returned to Turkey for posttransplantation follow-up. The aims of this study are to evaluate the long-term results of renal transplantation from nonrelated living donors in Turkish patients with end-stage renal disease and to discuss the ethical and social aspects of nonrelated kidney donation. One hundred and twenty-seven patients (89 males, 38 females; mean age 38.1, range 17-63 years) were investigated retrospectively. None of the patients went to Bombay on our advice. All transplantations were performed between 1991 and 1995. The mean follow-up period after transplantation was 34.2 (range 1-68) months. Graft survival rates were 85, 83, and 57% after 3 months and 1 and 5 years, respectively. Patient survival rates were 94, 93, and 92% after 3 months and 1 and 5 years, respectively. Seven patients died within the first 3 months after the transplantation. Surgical problems, infections, acute rejection, ciclosporin nephrotoxicity, and hepatic problems were common complications. We conclude that medical and surgical complications occur frequently in paid kidney transplantation, but most of these complications can be prevented by adequate preoperative management, and precautionary measures should be taken to prevent commercialization of renal transplantation before the spread of emotionally related living kidney donation.
URI: https://hdl.handle.net/11499/5641
https://doi.org/10.1159/000045091
ISSN: 0028-2766
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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