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https://hdl.handle.net/11499/5642
Title: | Comparison of amoxicillin with second and third generation cephalosporins in the treatment of acute otitis media | Authors: | Kara, Cüneyt Orhan Ozuer, M.Z. Kilic, I. Yalcin, A.N. Ergin, H. |
Keywords: | Acute otitis media Amoxicillin Ceftriaxone Cefuroxime axetil amoxicillin ceftriaxone cefuroxime axetil cephalosporin derivative paracetamol article child clinical trial controlled clinical trial controlled study diarrhea drug efficacy drug tolerability fever human infant intramuscular drug administration major clinical study oral drug administration otitis media randomized controlled trial rash |
Abstract: | The aim of the present study was to compare the efficacy and the tolerability of three different antibiotic regimens for the treatment of acute otitis media in paediatric patients. 75 children, age range 6 months-6 years, divided into three groups, were involved in the study, each group consisting of 25 randomly assigned children (Group 1, amoxicillin 40 mg/kg tid per os for 10 days; Group 2, cefuroxime axetil 30 mg/kg bid per os for 10 days; ceftriaxone 50 mg/kg single-dose i.m.). No statistically significant difference was noted in the clinical efficacy among the different groups. Although amoxicillin is the drug of choice in paediatric otitis media, single dose ceftriaxone might be considered as an interesting alternative regimen when ease of administration and cost of therapy are considered. | URI: | https://hdl.handle.net/11499/5642 | ISSN: | 1124-9390 |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu |
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