Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/5642
Title: Comparison of amoxicillin with second and third generation cephalosporins in the treatment of acute otitis media
Authors: Kara, Cüneyt Orhan
Ozuer, M.Z.
Kilic, I.
Yalcin, A.N.
Ergin, H.
Keywords: Acute otitis media
Amoxicillin
Ceftriaxone
Cefuroxime axetil
amoxicillin
ceftriaxone
cefuroxime axetil
cephalosporin derivative
paracetamol
article
child
clinical trial
controlled clinical trial
controlled study
diarrhea
drug efficacy
drug tolerability
fever
human
infant
intramuscular drug administration
major clinical study
oral drug administration
otitis media
randomized controlled trial
rash
Abstract: The aim of the present study was to compare the efficacy and the tolerability of three different antibiotic regimens for the treatment of acute otitis media in paediatric patients. 75 children, age range 6 months-6 years, divided into three groups, were involved in the study, each group consisting of 25 randomly assigned children (Group 1, amoxicillin 40 mg/kg tid per os for 10 days; Group 2, cefuroxime axetil 30 mg/kg bid per os for 10 days; ceftriaxone 50 mg/kg single-dose i.m.). No statistically significant difference was noted in the clinical efficacy among the different groups. Although amoxicillin is the drug of choice in paediatric otitis media, single dose ceftriaxone might be considered as an interesting alternative regimen when ease of administration and cost of therapy are considered.
URI: https://hdl.handle.net/11499/5642
ISSN: 1124-9390
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu

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