Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/5666
Title: Effects of adrenal and renal metabolites on testicular temperature and morphology in varicocele
Authors: Aybek, Zafer
Çallı, Neşe
Düzcan, Ender
Bayramoglu, Hatice
Yonguç, Tarık
Keywords: Adrenal metabolites
Temperature
Testicular histology
Varicocele
adrenal gland
adrenalectomy
animal experiment
animal model
animal tissue
article
controlled study
desquamation
epididymis
germ cell
histology
kidney
leydig cell
male
metabolite
morphology
nephrectomy
nonhuman
rat
seminal vesicle
sperm
spermatic vein
temperature
testis
testis biopsy
varicocele
Abstract: The aim of this study was to research for the validity of the hypothesis, which claims that the reflux of renal and adrenal metabolites by internal spermatic vein through testis causes morphological changes. The study was planned for three groups as sham [Group I, n:5], experimantally induced left varicocele (Group II, n:7), experimantally induced left varicocele + left adrenalectomy + left nephrectomy [Group III: n:9), containing 21 adolescent rats, totally. Ten weeks after the operation the wheights of vesicula seminalis, epididiym, testis and intratesticular-intraperitoneal temperatures of each rat were measured. Additionally epididimal sperm aspiration was performed and testicular biopsy specimens were obtained for histological examination. The differences between intraabdominal and intratesticular temperatures (delta T) were statistically significant between the groups II-III and I (p < 0.05). Histological examination showed that the germ cell desquamation was present in 5 (71.4%) and 1 (11.1%) of the rats in-groups II and III, respectively. Also, Leydig cell changes were more prominent in groups II and III than group I. The results of our study have shown that although elevated intratesticular temperature was responsible for the morphological alteration of testicular tissue in varicocele, some adrenal and/or renal factors also contribute to this process.
URI: https://hdl.handle.net/11499/5666
ISSN: 1300-2996
Appears in Collections:Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection

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