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https://hdl.handle.net/11499/56872
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ozer, U. | - |
dc.contributor.author | Yucens, B. | - |
dc.contributor.author | Tumkaya, S. | - |
dc.date.accessioned | 2024-03-23T13:10:02Z | - |
dc.date.available | 2024-03-23T13:10:02Z | - |
dc.date.issued | 2024 | - |
dc.identifier.issn | 0022-3956 | - |
dc.identifier.uri | https://doi.org/10.1016/j.jpsychires.2024.02.005 | - |
dc.identifier.uri | https://hdl.handle.net/11499/56872 | - |
dc.description.abstract | High-frequency deep transcranial magnetic stimulation (dTMS) targeting the medial prefrontal cortex (mPFC) and the anterior cingulate cortex (ACC) with an H-coil has received approval from the Food and Drug Administration for the treatment of obsessive-compulsive disorder (OCD). Nevertheless, there is limited evidence regarding the efficacy of a similar procedure performed using a double-cone coil or in an accelerated regimen. In this study, patients in the active TMS group (n = 14) underwent stimulation of the mPFC and ACC twice daily at a frequency of 20 Hz for three weeks, using a double-cone coil. The same procedure was applied to the control group (n = 15) using a placebo coil. Throughout the study, the patients continued their antidepressant and/or antipsychotic treatments at the same dose. Following treatment, the active TMS group exhibited a more significant reduction in Yale-Brown Obsessive-Compulsive Scale scores (pre-treatment: 25.36 ± 5.4, post-treatment: 18.43 ± 6.86) and Hamilton Anxiety Rating Scale scores (pre-treatment: 10.6 ± 3.5, post-treatment: 6.7 ± 2.7) compared to the sham TMS group. However, there was no statistically significant reduction in symmetry-related obsessive-compulsive symptoms in the TMS group compared to the sham TMS group. dTMS applied to the mPFC and ACC, using a double-cone coil at a 20-Hz frequency twice daily for three weeks, was found to be effective as an adjunctive treatment for treatment-resistant OCD. © 2024 Elsevier Ltd | en_US |
dc.language.iso | en | en_US |
dc.publisher | Elsevier Ltd | en_US |
dc.relation.ispartof | Journal of Psychiatric Research | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Accelerated TMS | en_US |
dc.subject | Deep TMS | en_US |
dc.subject | Double-cone coil | en_US |
dc.subject | Obsessive-compulsive disorder | en_US |
dc.subject | Symmetry | en_US |
dc.subject | TMS | en_US |
dc.subject | controlled study | en_US |
dc.subject | double blind procedure | en_US |
dc.subject | human | en_US |
dc.subject | obsessive compulsive disorder | en_US |
dc.subject | physiology | en_US |
dc.subject | prefrontal cortex | en_US |
dc.subject | procedures | en_US |
dc.subject | randomized controlled trial | en_US |
dc.subject | transcranial magnetic stimulation | en_US |
dc.subject | treatment outcome | en_US |
dc.subject | Double-Blind Method | en_US |
dc.subject | Humans | en_US |
dc.subject | Obsessive-Compulsive Disorder | en_US |
dc.subject | Prefrontal Cortex | en_US |
dc.subject | Transcranial Magnetic Stimulation | en_US |
dc.subject | Treatment Outcome | en_US |
dc.title | Efficacy of accelerated deep transcranial magnetic stimulation wi̇th double cone coi̇l in obsessive-compulsive disorder: A double-blind, placebo-controlled study | en_US |
dc.type | Article | en_US |
dc.identifier.volume | 171 | en_US |
dc.identifier.startpage | 325 | en_US |
dc.identifier.endpage | 331 | en_US |
dc.department | Pamukkale University | en_US |
dc.identifier.doi | 10.1016/j.jpsychires.2024.02.005 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.authorscopusid | 58876296300 | - |
dc.authorscopusid | 56331858500 | - |
dc.authorscopusid | 24449617000 | - |
dc.identifier.pmid | 38342033 | en_US |
dc.identifier.scopus | 2-s2.0-85184618086 | en_US |
dc.identifier.wos | WOS:001181540300001 | en_US |
dc.institutionauthor | … | - |
item.openairetype | Article | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.languageiso639-1 | en | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | No Fulltext | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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