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https://hdl.handle.net/11499/57043
Title: | The association of milk and multiple food avoidance with growth parameters in infants and children | Authors: | Sackesen, C. Buyuktiryaki, B. Gokce, T. Gogebakan, E. Gundogdu, B.S. Eltan, S.B. Karakoc-Aydiner, E. Yilmaz, Ebru Arik Can, Ceren Cengiz, Hilal Unlugedik, Ozlem Celik, Nevin Incir, Said Mutlu, Gul Yesiltepe Yildirim, Damla Ozel, Hulya Gokmen Hatun, Sukru |
Publisher: | American College of Allergy, Asthma and Immunology | Abstract: | Background: Recent studies reported that strict avoidance of milk products in cow's milk allergy (CMA) affects growth and bone turnover, causing negative calcium balance and changes in bone metabolism. Objective: To investigate biochemical parameters to predict bone turnover and its relations with height and weight measurements and nutritional intake. Methods: Height, weight, and body mass index z scores were plotted for age according to the World Health Organization. A 3-consecutive day food record was analyzed for nutritional values of foods. The blood levels of calcium, phosphorus, alkaline phosphatase, vitamin D, and parathyroid hormone (PTH) were determined. Results: The study included 69 controls, 66 children with isolated CMA, and 59 children with multiple food allergy (FA). The z scores for weight, height, and body mass index were lower in isolated CMA and multiple FA groups than controls (P < .001, P = .004, and P = .002, respectively). The nutritional intakes of protein, fat, carbohydrates, vitamins B2 and B12, niacin, calcium, and phosphorus were significantly lower in isolated CMA and multiple FA than controls. In infants (≤2 years of age), although blood calcium level was in normal range, it was significantly lower in isolated CMA and multiple FA than in controls (P < .001). In children older than 2 years, PTH level was significantly higher in isolated CMA and multiple FA groups than in controls (P = .003). Conclusion: Our study revealed that children with isolated CMA and multiple FA had a high nutrition gap, growth deceleration, and unbalanced bone metabolism, as illustrated by low blood calcium and elevated PTH levels. © 2024 American College of Allergy, Asthma & Immunology | URI: | https://doi.org/10.1016/j.anai.2024.02.023 https://hdl.handle.net/11499/57043 |
ISSN: | 1081-1206 |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu |
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