Antibiotic resistance pattern of pseudomonas species in surgical wound infections

Abstract

Surgical wound infections caused by Pseudomonas species constitute an important group of nosocomial infections causing high morbidity and mortality. The antimicrobial resistance of Pseudomonas species isolated from surgical wound infections between March 1991, and January 1994 has been evaluated. Predisposing factors in these surgical wound infections were; trauma, fractures, operations, burns, diabetus-mellitus, and malignancies. By using the disc diffusion method, antibiotic resistance of 57 Pseudomonas species against Mezlocillin, Piperacillin, Cefoperazone, Cefotaxime, Gentamycin, Tobramycin, Netilmicin, Amikacin, Ciprofloxacin, and Ofloxacin was investigated. Mezlocillin, Piperacillin, Gentamycin, Cefotaxime and Cefoperazone were found to be the least effective antibiotics with resistance rates of 91.8%, 73.6%, 68.0%, 56.0%, and 34.2%, respectively. Ciprofloxacin and 0floxacin were found to be the most effective antibiotics with resistance rates of 2.0%, and 9.3%, respectively. Ciprofloxacin, Ofloxacin, and Netilmicin were observed as the most effective antibacterial agents against Pseudomonas species isolated from surgical wound infections.