Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/57585
Title: Determining the Risk Factors for Anastomotic Stricture Development after Esophageal Atresia Repair: Results from the Turkish Esophageal Atresia Registry
Authors: Öztorun, Can İhsan
Ulukaya Durakbasa, Çiğdem
Soyer, Tutku
Özcan, Coşkun
Fırıncı, Binali
Demirel, Berat Dilek
Çiftci, İlhan
Parlak, Ayse
Oztan, Mustafa Onur
Göllü, Gülnur
Akkoyun, Ibrahim
Karaman, Ayşe
Gul, Cengiz
Şalcl, Gül
İlhan, Hüseyin
Oral, Akgun
Özcan, Rahşan
Özaydln, Seyithan
Kilic, Seref Selcuk
Klyan, Gursu
Erdem, Ali Onur
Uzunlu, Osman
Yildiz, Abdullah
Ozcakir, Esra
Erturk, Nazile
Erginel, Başak
Öztaş, Tülin
Atlcl, Ahmet
Mert, Mehmet
Samsum, Hakan
Ozen, Mehmet Ali
Aydln, Emrah
Sancar, Serpil
Keywords: esophageal atresia
tracheoesophageal fistula
anastomotic strictures
risk factors
Tracheoesophageal Fistula
Complications
Children
Thoracotomy
Population
Prevalence
Management
Survival
Outcomes
Publisher: Georg Thieme Verlag Kg
Abstract: Introduction Anastomotic stricture (AS) is the second most common complication after esophageal atresia (EA) repair. We aimed to evaluate the data in the Turkish Esophageal Atresia Registry to determine the risk factors for AS development after EA repair in a large national cohort of patients. Methods The data between 2015 and 2021 were evaluated. Patients were enrolled into two groups according to the occurrence of AS. Patients with AS (AS group) and without AS (non-AS group) were compared according to demographic and operative features, postoperative intubation status, and postoperative complications, such as anastomotic leaks, fistula recanalization, and the presence of gastroesophageal reflux (GER). A multivariable logistic regression analysis was performed to define the risk factors for the development of AS after EA repair. Results Among the 713 cases, 144 patients (20.19%) were enrolled into the AS group and 569 (79.81%) in the non-AS group. The multivariable logistic regression showed that, being a term baby (odds ratio [OR]: 1.706; p = 0.006), having a birth weight over 2,500 g (OR: 1.72; p = 0.006), presence of GER (OR: 5.267; p < 0.001), or having a recurrent tracheoesophageal fistula (TEF, OR: 4.363; p = 0.006) were the risk factors for the development of AS. Conclusions The results of our national registry demonstrate that 20% of EA patients developed AS within their first year of life. In patients with early primary anastomosis, birth weight greater than 2,500 g and presence of GER were risk factors for developing AS. When patients with delayed anastomosis were included, in addition to the previous risk factors, being a term baby, and having recurrent TEF also became risk factors.
URI: https://doi.org/10.1055/a-2340-9078
https://hdl.handle.net/11499/57585
ISSN: 0939-7248
1439-359X
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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