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https://hdl.handle.net/11499/57765
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DC Field | Value | Language |
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dc.contributor.author | Gültekin, Aziz | - |
dc.contributor.author | Şengöz, Tarık | - |
dc.contributor.author | Demirezen, Samiye | - |
dc.contributor.author | Yuksel, Dogangun | - |
dc.date.accessioned | 2024-09-08T11:22:27Z | - |
dc.date.available | 2024-09-08T11:22:27Z | - |
dc.date.issued | 2024 | - |
dc.identifier.issn | 2146-1414 | - |
dc.identifier.issn | 2147-1959 | - |
dc.identifier.uri | https://doi.org/10.4274/mirt.galenos.2024.48254 | - |
dc.identifier.uri | https://hdl.handle.net/11499/57765 | - |
dc.description.abstract | Objectives: Meckel scintigraphy is used to diagnose Meckel's diverticulum. Previously, premedication with ranitidine was the most frequently used method to increase the accuracy of scintigraphy. However, ranitidine can no longer be used because it is banned by the Food and Drug Administration. The aim of this study was to investigate the usability of pantoprazole as a premedication instead of ranitidine in Meckel scintigraphy. Methods: Twelve New Zealand rabbits were used in this experimental study. Rabbits were divided into two groups: pantoprazole and control. Six rabbits were premedicated with pantoprazole for three days. Meckel scintigraphy was performed on all rabbits. Counts were made and compared by drawing regions of interest from the stomach walls. Results: According to the findings of this experimental study, pantoprazole significantly increased Tc-99m-pertechnetate uptake in the stomach of rabbits on both visual and quantitative evaluation. Conclusion: Pantoprazole increases the gastric wall uptake of Tc-99m-pertechnetate in rabbits and is a potential drug for premedication in Meckel scintigraphy. | en_US |
dc.description.sponsorship | Ethics Ethics Committee Approval: This preclinical study was approved by the Pamukkale University Animal Experimentation Ethics Committee (no: PAUHDEK-2021/48, date: 24.02.2022) . All national and international directives were complied with during the experiments. Informed Consent: Animal experimental study. Authorship Contributions Surgical and Medical Practices: A.G., S.D., Concept: A.G., Design: A.G., T.S., Data Collection or Processing: A.G., S.D., Analysis or Interpretation: T.S., D.Y., Literature Search: A.G., Writing: A.G., D.Y. Conflict of Interest: No conflict of interest was declared by the authors. Financial Disclosure: The authors declared that this study has received no financial support. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Galenos Publ House | en_US |
dc.relation.ispartof | Molecular Imaging and Radionuclide Therapy | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Meckel's diverticulum | en_US |
dc.subject | Meckel scintigraphy | en_US |
dc.subject | preclinical imaging | en_US |
dc.subject | pantoprazole | en_US |
dc.subject | premedication for Meckel scan | en_US |
dc.subject | Ectopic Gastric-Mucosa | en_US |
dc.subject | Pharmacological Interventions | en_US |
dc.subject | Diverticulum | en_US |
dc.subject | Cimetidine | en_US |
dc.title | Can pantoprazole be used for premedication in meckel scintigraphy? | en_US |
dc.type | Article | en_US |
dc.identifier.volume | 33 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.startpage | 90 | en_US |
dc.identifier.endpage | 93 | en_US |
dc.department | Pamukkale University | en_US |
dc.identifier.doi | 10.4274/mirt.galenos.2024.48254 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.authorscopusid | 57213854346 | - |
dc.authorscopusid | 56667569600 | - |
dc.authorscopusid | 59248798100 | - |
dc.authorscopusid | 6701446280 | - |
dc.identifier.pmid | 38949418 | en_US |
dc.identifier.scopus | 2-s2.0-85200610805 | en_US |
dc.identifier.trdizinid | 1282709 | en_US |
dc.identifier.wos | WOS:001272711600003 | en_US |
dc.institutionauthor | … | - |
item.cerifentitytype | Publications | - |
item.fulltext | With Fulltext | - |
item.grantfulltext | open | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.languageiso639-1 | en | - |
item.openairetype | Article | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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