Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/57765
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dc.contributor.authorGültekin, Aziz-
dc.contributor.authorŞengöz, Tarık-
dc.contributor.authorDemirezen, Samiye-
dc.contributor.authorYuksel, Dogangun-
dc.date.accessioned2024-09-08T11:22:27Z-
dc.date.available2024-09-08T11:22:27Z-
dc.date.issued2024-
dc.identifier.issn2146-1414-
dc.identifier.issn2147-1959-
dc.identifier.urihttps://doi.org/10.4274/mirt.galenos.2024.48254-
dc.identifier.urihttps://hdl.handle.net/11499/57765-
dc.description.abstractObjectives: Meckel scintigraphy is used to diagnose Meckel's diverticulum. Previously, premedication with ranitidine was the most frequently used method to increase the accuracy of scintigraphy. However, ranitidine can no longer be used because it is banned by the Food and Drug Administration. The aim of this study was to investigate the usability of pantoprazole as a premedication instead of ranitidine in Meckel scintigraphy. Methods: Twelve New Zealand rabbits were used in this experimental study. Rabbits were divided into two groups: pantoprazole and control. Six rabbits were premedicated with pantoprazole for three days. Meckel scintigraphy was performed on all rabbits. Counts were made and compared by drawing regions of interest from the stomach walls. Results: According to the findings of this experimental study, pantoprazole significantly increased Tc-99m-pertechnetate uptake in the stomach of rabbits on both visual and quantitative evaluation. Conclusion: Pantoprazole increases the gastric wall uptake of Tc-99m-pertechnetate in rabbits and is a potential drug for premedication in Meckel scintigraphy.en_US
dc.description.sponsorshipEthics Ethics Committee Approval: This preclinical study was approved by the Pamukkale University Animal Experimentation Ethics Committee (no: PAUHDEK-2021/48, date: 24.02.2022) . All national and international directives were complied with during the experiments. Informed Consent: Animal experimental study. Authorship Contributions Surgical and Medical Practices: A.G., S.D., Concept: A.G., Design: A.G., T.S., Data Collection or Processing: A.G., S.D., Analysis or Interpretation: T.S., D.Y., Literature Search: A.G., Writing: A.G., D.Y. Conflict of Interest: No conflict of interest was declared by the authors. Financial Disclosure: The authors declared that this study has received no financial support.en_US
dc.language.isoenen_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofMolecular Imaging and Radionuclide Therapyen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMeckel's diverticulumen_US
dc.subjectMeckel scintigraphyen_US
dc.subjectpreclinical imagingen_US
dc.subjectpantoprazoleen_US
dc.subjectpremedication for Meckel scanen_US
dc.subjectEctopic Gastric-Mucosaen_US
dc.subjectPharmacological Interventionsen_US
dc.subjectDiverticulumen_US
dc.subjectCimetidineen_US
dc.titleCan pantoprazole be used for premedication in meckel scintigraphy?en_US
dc.typeArticleen_US
dc.identifier.volume33en_US
dc.identifier.issue2en_US
dc.identifier.startpage90en_US
dc.identifier.endpage93en_US
dc.departmentPamukkale Universityen_US
dc.identifier.doi10.4274/mirt.galenos.2024.48254-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.authorscopusid57213854346-
dc.authorscopusid56667569600-
dc.authorscopusid59248798100-
dc.authorscopusid6701446280-
dc.identifier.pmid38949418en_US
dc.identifier.scopus2-s2.0-85200610805en_US
dc.identifier.trdizinid1282709en_US
dc.identifier.wosWOS:001272711600003en_US
dc.institutionauthor-
item.cerifentitytypePublications-
item.fulltextWith Fulltext-
item.grantfulltextopen-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.languageiso639-1en-
item.openairetypeArticle-
crisitem.author.dept14.02. Internal Medicine-
crisitem.author.dept14.02. Internal Medicine-
crisitem.author.dept14.02. Internal Medicine-
crisitem.author.dept14.02. Internal Medicine-
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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