Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/58212
Title: Green Synthesis of Electroactive Magnesium Ferrite Nanoparticles for the Selective Determination of Mefenamic Acid in Blood, Pharmaceutical Products, and Wastewater
Authors: Perveen, Saima
Baig, Jameel Ahmed
Sherazi, Syed Tufail Hussain
Memon, Shahabuddin
Akhtar, Khalil
Hussain, Sajjad
Abbasi, Fahad
Keywords: Blood analysis
differential pulse voltammetry
green synthesis
mefenamic acid
MgFe4O7-NPs
Simultaneous Electrochemical Detection
Nanostructures
Sensor
Metal
Publisher: Taylor & Francis Inc
Abstract: Mefenamic acid (MNA) treats sports injuries, rheumatoid arthritis, and osteoarthritis. However, improper use/disposal of MNA results in the accumulation of toxic metabolites that may serious disease. The purpose of this study is to fabricate a nano ferrite-based electrochemical sensor for robust, and sensitive determination of MNA. Magnesium ferrite nanoparticles (MgFe4O7-NPs) were synthesized using a green approach using a Mentha leaf extract. The analytical characterization of MgFe4O7-NPs displayed a hexagonal structure and a particle size of less than 21 nm with rough and porous morphology. The synthesized MgFe4O7-NPs were used to fabricate an electrochemical sensor by modifying a glassy carbon electrode (MgFe4O7-NPs/GCE). The cyclic voltammetry (CV) characterization of the electrode confirms excellent redox and diffusion control for electroactive species. Thus, the MgFe4O7-NPs/GCE was used to determine MNA by differential pulse voltammetry (DPV). The results showed a linear relationship between oxidation peak current and concentration of MNA from 10 x 10(-9) to 2.30 x 10(-4) M (R-2 = 0.9918) with a detection limit of 1.12 x 10(-9) M. The analytical performance of the fabricated sensor has been evaluated for MNA in blood samples, pharmaceutical tablets, and water samples with satisfactory results.
URI: https://doi.org/10.1080/00032719.2024.2413455
https://hdl.handle.net/11499/58212
ISSN: 0003-2719
1532-236X
Appears in Collections:Fen Fakültesi Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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