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https://hdl.handle.net/11499/5825
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DC Field | Value | Language |
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dc.contributor.author | Yüksel, Doğangün | - |
dc.contributor.author | Kıraç, Fatma Suna | - |
dc.contributor.author | Yaylalı, Olga | - |
dc.contributor.author | Demiray Uguz, I. | - |
dc.date.accessioned | 2019-08-16T12:02:42Z | - |
dc.date.available | 2019-08-16T12:02:42Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 1300-0144 | - |
dc.identifier.uri | https://hdl.handle.net/11499/5825 | - |
dc.identifier.uri | https://doi.org/10.3906/sag-1010-1232 | - |
dc.description.abstract | Aim: To investigate the prognostic role of Tc-99m pertechnetate thyroid scintigraphy pretreatment in patients with toxic multinodular goiters (TMNG) who were then treated with fixed I-131 doses. Materials and methods: We retrospectively evaluated 28 patients (18 females and 10 males; mean ± SD = 63 ± 11 years) that were treated with 740 megabecquerels (MBq) of I-131 for TMNG. Information, including age, Tc-99m pertechnetate thyroid scintigraphy and ultrasonography findings, antithyroid medication, thyroid hormone profile, and clinical status before treatment, was recorded. Th e regions of interest were drawn over the hot nodules, salivary glands, and the background on the anterior thyroid images. Th e net nodule counts, net salivary counts, nodule-to-salivary ratios, and nodule-to-background ratios were then calculated. The data were statistically compared for the hypothyroid and euthyroid patient groups after radioiodine treatment. Results: In the study group, the mean follow-up period was 7 ± 2 months (range: 6-12 months). We detected hyperthyroidism in 1 patient, euthyroidism in 19 patients, and hypothyroidism in 8 patients. Th e pretreatment mean net nodule counts (34.79 ± 14.06 counts) in the patients that developed hypothyroidism were significantly higher than in those patients that developed euthyroidism (26.80 ± 11.04 counts) (P = 0.014). The other 3 parameters did not show significant differences between the 2 groups. Conclusion: Th e Tc-99m pertechnetate uptake level of hot nodules calculated from the pretreatment of thyroid scintigraphy in patients with TMNG treated with a fixed 740-MBq I-131 dose may predict early hypothyroidism in patients. © TÜBİTAK. | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Turkish Journal of Medical Sciences | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | I-131 | en_US |
dc.subject | Radioiodine | en_US |
dc.subject | Tc-99m pertechnetate | en_US |
dc.subject | Toxic multinodular goiter | en_US |
dc.subject | iodine 131 | en_US |
dc.subject | pertechnetic acid tc 99m | en_US |
dc.subject | propylthiouracil | en_US |
dc.subject | adult | en_US |
dc.subject | aged | en_US |
dc.subject | article | en_US |
dc.subject | clinical article | en_US |
dc.subject | clinical assessment | en_US |
dc.subject | controlled study | en_US |
dc.subject | drug tumor level | en_US |
dc.subject | echography | en_US |
dc.subject | euthyroidism | en_US |
dc.subject | female | en_US |
dc.subject | human | en_US |
dc.subject | hypothyroidism | en_US |
dc.subject | image analysis | en_US |
dc.subject | male | en_US |
dc.subject | outcome assessment | en_US |
dc.subject | prognosis | en_US |
dc.subject | retrospective study | en_US |
dc.subject | salivary gland | en_US |
dc.subject | thyroid nodule | en_US |
dc.subject | thyroid scintiscanning | en_US |
dc.subject | toxic goiter | en_US |
dc.subject | treatment response | en_US |
dc.title | Prognostic role of Tc-99m pertechnetate thyroid scintigraphy prior to fixed-dose radioiodine therapy of toxic multinodular goiters | en_US |
dc.type | Article | en_US |
dc.identifier.volume | 41 | en_US |
dc.identifier.issue | 6 | en_US |
dc.identifier.startpage | 981 | en_US |
dc.identifier.endpage | 988 | en_US |
dc.identifier.doi | 10.3906/sag-1010-1232 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.scopus | 2-s2.0-80155129110 | en_US |
dc.identifier.trdizinid | 127269 | en_US |
dc.identifier.wos | WOS:000298197700005 | en_US |
dc.identifier.scopusquality | Q3 | - |
dc.owner | Pamukkale University | - |
item.cerifentitytype | Publications | - |
item.languageiso639-1 | en | - |
item.grantfulltext | open | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | With Fulltext | - |
item.openairetype | Article | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
Appears in Collections: | Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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