Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/5825
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dc.contributor.authorYüksel, Doğangün-
dc.contributor.authorKıraç, Fatma Suna-
dc.contributor.authorYaylalı, Olga-
dc.contributor.authorDemiray Uguz, I.-
dc.date.accessioned2019-08-16T12:02:42Z-
dc.date.available2019-08-16T12:02:42Z-
dc.date.issued2011-
dc.identifier.issn1300-0144-
dc.identifier.urihttps://hdl.handle.net/11499/5825-
dc.identifier.urihttps://doi.org/10.3906/sag-1010-1232-
dc.description.abstractAim: To investigate the prognostic role of Tc-99m pertechnetate thyroid scintigraphy pretreatment in patients with toxic multinodular goiters (TMNG) who were then treated with fixed I-131 doses. Materials and methods: We retrospectively evaluated 28 patients (18 females and 10 males; mean ± SD = 63 ± 11 years) that were treated with 740 megabecquerels (MBq) of I-131 for TMNG. Information, including age, Tc-99m pertechnetate thyroid scintigraphy and ultrasonography findings, antithyroid medication, thyroid hormone profile, and clinical status before treatment, was recorded. Th e regions of interest were drawn over the hot nodules, salivary glands, and the background on the anterior thyroid images. Th e net nodule counts, net salivary counts, nodule-to-salivary ratios, and nodule-to-background ratios were then calculated. The data were statistically compared for the hypothyroid and euthyroid patient groups after radioiodine treatment. Results: In the study group, the mean follow-up period was 7 ± 2 months (range: 6-12 months). We detected hyperthyroidism in 1 patient, euthyroidism in 19 patients, and hypothyroidism in 8 patients. Th e pretreatment mean net nodule counts (34.79 ± 14.06 counts) in the patients that developed hypothyroidism were significantly higher than in those patients that developed euthyroidism (26.80 ± 11.04 counts) (P = 0.014). The other 3 parameters did not show significant differences between the 2 groups. Conclusion: Th e Tc-99m pertechnetate uptake level of hot nodules calculated from the pretreatment of thyroid scintigraphy in patients with TMNG treated with a fixed 740-MBq I-131 dose may predict early hypothyroidism in patients. © TÜBİTAK.en_US
dc.language.isoenen_US
dc.relation.ispartofTurkish Journal of Medical Sciencesen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectI-131en_US
dc.subjectRadioiodineen_US
dc.subjectTc-99m pertechnetateen_US
dc.subjectToxic multinodular goiteren_US
dc.subjectiodine 131en_US
dc.subjectpertechnetic acid tc 99men_US
dc.subjectpropylthiouracilen_US
dc.subjectadulten_US
dc.subjectageden_US
dc.subjectarticleen_US
dc.subjectclinical articleen_US
dc.subjectclinical assessmenten_US
dc.subjectcontrolled studyen_US
dc.subjectdrug tumor levelen_US
dc.subjectechographyen_US
dc.subjecteuthyroidismen_US
dc.subjectfemaleen_US
dc.subjecthumanen_US
dc.subjecthypothyroidismen_US
dc.subjectimage analysisen_US
dc.subjectmaleen_US
dc.subjectoutcome assessmenten_US
dc.subjectprognosisen_US
dc.subjectretrospective studyen_US
dc.subjectsalivary glanden_US
dc.subjectthyroid noduleen_US
dc.subjectthyroid scintiscanningen_US
dc.subjecttoxic goiteren_US
dc.subjecttreatment responseen_US
dc.titlePrognostic role of Tc-99m pertechnetate thyroid scintigraphy prior to fixed-dose radioiodine therapy of toxic multinodular goitersen_US
dc.typeArticleen_US
dc.identifier.volume41en_US
dc.identifier.issue6en_US
dc.identifier.startpage981en_US
dc.identifier.endpage988en_US
dc.identifier.doi10.3906/sag-1010-1232-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.scopus2-s2.0-80155129110en_US
dc.identifier.trdizinid127269en_US
dc.identifier.wosWOS:000298197700005en_US
dc.identifier.scopusqualityQ3-
dc.ownerPamukkale University-
item.openairetypeArticle-
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextWith Fulltext-
item.grantfulltextopen-
crisitem.author.dept14.02. Internal Medicine-
crisitem.author.dept14.02. Internal Medicine-
crisitem.author.dept14.02. Internal Medicine-
crisitem.author.dept14.02. Internal Medicine-
Appears in Collections:Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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