Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/58954
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dc.contributor.authorDusunceli, Ibrahimhalil-
dc.contributor.authorSargin, Zeynep Gok-
dc.contributor.authorCelik, Umut-
dc.contributor.authorSargin, Fatih-
dc.date.accessioned2025-02-20T19:13:19Z-
dc.date.available2025-02-20T19:13:19Z-
dc.date.issued2025-
dc.identifier.issn1752-0363-
dc.identifier.issn1752-0371-
dc.identifier.urihttps://doi.org/10.1080/17520363.2025.2459596-
dc.identifier.urihttps://hdl.handle.net/11499/58954-
dc.description.abstractAim: Ulcerative colitis (UC) is an incurable disease represented by relapse and remission. Noninvasive biomarkers are required to predict disease activation. This study aimed to identify noninvasive biomarkers, such as the c-reactive protein-albumin (CRP/ALB) ratio, platelet-lymphocyte ratio (PLR), and neutrophil-lymphocyte ratio (NLR), that might forecast disease activation in UC. Methods: This retrospective study included 443 participants: 192 patients with active UC, 166 in remission, and 85 healthy controls. Mayo Endoscopic Subscore was employed to assess endoscopic disease activity. Serum CRP, erythrocyte sedimentation rate (ESR), ALB levels, and complete blood count characteristics were documented. Three ratios of inflammation-related indicators were identified as CRP/ALB, PLR, and NLR. Results: A positive correlation was found between ESR, CRP, neutrophil count, platelet count, levels of CRP/ALB, PLR, NLR, and endoscopic activity. The CRP/ALB ratio demonstrated more efficacy than the NLR and PLR in differentiating the UC patients from the controls (p = 0.007, p = 0.003, respectively) and the active group from the remission group (p < 0.001, p < 0.001, respectively). Regression analysis revealed that the CRP/ALB was significantly able to distinguish active UC from the remission group and the controls (p < 0.001, p < 0.001, respectively). Conclusion: The CRP/ALB ratio could be useful as an independent predictive biomarker for disease activity in UC.en_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectUlcerative Colitisen_US
dc.subjectDisease Activityen_US
dc.subjectC-Reactive Protein-Albumin Ratioen_US
dc.subjectPlatelet-Lymphocyte Ratioen_US
dc.subjectNeutrophil-Lymphocyte Ratioen_US
dc.titleThe ability of C-reactive protein-albumin ratio to predict disease activity in ulcerative colitisen_US
dc.typeArticleen_US
dc.departmentPamukkale Universityen_US
dc.identifier.doi10.1080/17520363.2025.2459596-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.authorscopusid57884011200-
dc.authorscopusid56905424400-
dc.authorscopusid58023161800-
dc.authorscopusid59168495800-
dc.identifier.pmid39887140-
dc.identifier.scopus2-s2.0-85216488365-
dc.identifier.wosWOS:001411557400001-
dc.identifier.scopusqualityQ3-
dc.description.woscitationindexScience Citation Index Expanded-
dc.identifier.wosqualityQ4-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.fulltextNo Fulltext-
item.languageiso639-1en-
item.cerifentitytypePublications-
item.openairetypeArticle-
crisitem.author.dept14.01. Surgical Medicine-
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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