Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/60327
Title: Cytotoxicity, Apoptotic, Antioxidant and Antimicrobial Activity of Dictyota Dichotoma (Hudson) Jv Lamouroux 1809 Collected From Antalya Coast, Turkiye
Authors: Arslan, Sevki
Abdelsalam, Amine Hafis
Kizildogan, Aslihan Kurt
Otur, Cigdem
Konus, Metin
Cetin, Dogan
Okudan, Emine Sukran
Keywords: Dictyota Dichotoma
Cytotoxic Activity
Apoptosis Antimicrobial Potential
Antioxidant Activity
Gene Expression
Publisher: Pleiades Publishing inc
Abstract: Current study was purposed to reveal the cytotoxic, apoptotic, antimicrobial and antioxidant potentials of oil extracted from Dictyota dichotoma (Hudson) J.V. Lamouroux 1809 collected from Antalya coast of Turkiye. Dictyota dichotoma oil showed better cytotoxic activity towards two different adenocarcinoma cell lines (Caco-2 (8.83 mu g/mL) and LnCap (10.86 mu g/mL)) compared to HEK293 cells (non-cancerous). Annexin V/PI staining and qPCR studies revealed that oil caused induction of apoptosis. Dictyota dichotoma oil inhibited the growth of Aspergillus niger ATCC 16404 and Enterococcus faecalis ATCC 29212. Nevertheless, the lower antioxidant activity of Dictyota dichotoma oil was determined compared with trolox standard for both DPPH and ABTS assays (4.8 fold less). In conclusion, Dictyota dichotoma oil has a promising potential in medical usage.
URI: https://doi.org/10.1134/S1062359024608814
https://hdl.handle.net/11499/60327
ISSN: 1062-3590
1608-3059
Appears in Collections:WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

Show full item record



CORE Recommender

Google ScholarTM

Check




Altmetric


Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.