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https://hdl.handle.net/11499/60327
Title: | Cytotoxicity, Apoptotic, Antioxidant and Antimicrobial Activity of Dictyota Dichotoma (Hudson) Jv Lamouroux 1809 Collected From Antalya Coast, Turkiye | Authors: | Arslan, Sevki Abdelsalam, Amine Hafis Kizildogan, Aslihan Kurt Otur, Cigdem Konus, Metin Cetin, Dogan Okudan, Emine Sukran |
Keywords: | Dictyota Dichotoma Cytotoxic Activity Apoptosis Antimicrobial Potential Antioxidant Activity Gene Expression |
Publisher: | Pleiades Publishing inc | Abstract: | Current study was purposed to reveal the cytotoxic, apoptotic, antimicrobial and antioxidant potentials of oil extracted from Dictyota dichotoma (Hudson) J.V. Lamouroux 1809 collected from Antalya coast of Turkiye. Dictyota dichotoma oil showed better cytotoxic activity towards two different adenocarcinoma cell lines (Caco-2 (8.83 mu g/mL) and LnCap (10.86 mu g/mL)) compared to HEK293 cells (non-cancerous). Annexin V/PI staining and qPCR studies revealed that oil caused induction of apoptosis. Dictyota dichotoma oil inhibited the growth of Aspergillus niger ATCC 16404 and Enterococcus faecalis ATCC 29212. Nevertheless, the lower antioxidant activity of Dictyota dichotoma oil was determined compared with trolox standard for both DPPH and ABTS assays (4.8 fold less). In conclusion, Dictyota dichotoma oil has a promising potential in medical usage. | URI: | https://doi.org/10.1134/S1062359024608814 https://hdl.handle.net/11499/60327 |
ISSN: | 1062-3590 1608-3059 |
Appears in Collections: | WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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