18F-FDG PET/CT of a Multicentric Castleman Disease with Lymph Node and Skin Involvement

Abstract

Herein, we describe a rare case of multicentric Castleman disease with multiple lymph node and skin involvement. Ultrasonography of a 38-year-old patient with weakness and fever revealed multiple lymphadenopathies in both inguinal regions. Diagnosed via lymph node biopsy was Castleman's disease, a plasma cell variant. He was diagnosed with prurigo nodularis, lymphocytic vasculitis, and stasis dermatitis in the biopsies of skin lesions located in different regions. F-18-fluorodeoxyglucose positron emission tomography/computed tomography showed multiple hypermetabolic lymph nodes in the axilla, abdomen, pelvis, and both popliteal areas, multiple hypermetabolic skin thickenings, and skin lesions in both arms, legs, and feet.