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https://hdl.handle.net/11499/6052
Title: | Evaluation of the therapeutic use of antibiotics in Aegean Region hospitals of Turkey: A multicentric study | Authors: | Ozgenç, O. Genç, V.E. Ari, A.A. Sibel, E.L. Saçar, S. Ozunlu, H. Akgul, A. |
Keywords: | Antibiotic restriction policy appropriate antibiotic usage amikacin amoxicillin ampicillin antibiotic agent cefazolin cefoperazone cefotaxime cefprozil ceftazidime ceftizoxime ceftriaxone cefuroxime cilastatin ciprofloxacin fluconazole gentamicin imipenem itraconazole levofloxacin meropenem metronidazole moxifloxacin netilmicin penicillin G piperacillin sulbactam tazobactam teicoplanin adult article cross-sectional study drug screening drug use female human infection major clinical study male multicenter study physician prescription Turkey (republic) Adolescent Adult Aged Aged, 80 and over Anti-Bacterial Agents Drug Utilization Female Guideline Adherence Health Services Research Hospitals Humans Male Middle Aged Turkey Young Adult |
Abstract: | Purpose: The antibiotic restriction policy has been validated nationwide since February 2003 by the Ministry of Health because the excessive consumption of antimicrobials causes a high cost. The aim of this study was to evaluate the therapeutic use of antibiotics in Aegean Region hospitals and to assess the impact of this nationwide antibiotic restriction policy. This new policy is based on justification that the infectious disease (ID) physicians should be primarily responsible for the prescription of antimicrobials. Materials and Methods: Eight university and government hospitals were included in the study. The criteria of the Council for Appropriate and Rational Antibiotic Therapy (CARAT) were considered. Both patient-based and antibiotic-based analyses were performed. For the analysis of inappropriate use, logistic regression was modeled. Results: Therapeutic use was determined in 540 patients by a total of 29 ID physicians.In the study, 30.2% of the patients were given antimicrobials and empirically started antibiotics accounted for 79% cases of therapeutic antibiotic use, and 60% of those were inappropriate (P = 0.001). The appropriate use of ID level antibiotics (P = 0.000) were very compatible with other antimicrobial groups. Conclusion: The study shows that the Turkish government's new intervention policy on antimicrobial prescribing has been effective. | URI: | https://hdl.handle.net/11499/6052 https://doi.org/10.4103/0255-0857.81788 |
ISSN: | 0255-0857 |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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IndianJMedMicrobiol_2011_29_2_124_81788.pdf | 1.22 MB | Adobe PDF | View/Open |
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