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https://hdl.handle.net/11499/6053
Title: | Extrapulmonary involvement in patients with sarcoidosis in Turkey | Authors: | Okumus, G. Musellim, B. Cetinkaya, E. Turker, H. Uzaslan, E. Yenturk, E. Uzun, O. |
Keywords: | Clinical epidemiology Extrapulmonary involvement Sarcoidosis adult arthralgia arthritis article backache bone pain cardiovascular disease diarrhea dizziness dyspepsia erythema nodosum eye eye disease female gastrointestinal symptom headache heart palpitation hepatomegaly human joint swelling kidney disease lung lung sarcoidosis lymph node lymphadenopathy major clinical study male medical record review multicenter study myalgia neck tumor neurological complication paresthesia parotid gland priority journal range of motion sarcoidosis skin skin defect splenomegaly sweating Turkey (republic) xerostomia Adult Arthralgia Back Pain Eye Diseases Female Humans Incidence Lymph Nodes Male Middle Aged Prevalence Prospective Studies Skin Diseases Turkey |
Abstract: | Background and objective: Extrapulmonary sarcoidosis is common, and is almost always associated with concomitant thoracic involvement. Extrapulmonary manifestations vary on the basis of gender, age at presentation and ethnicity. The aim of this study was to investigate extrapulmonary involvement in patients with sarcoidosis in Turkey. Methods: This study was conducted by Turkish Thoracic Society Clinical Problems Study Group.New cases of sarcoidosis between 1 June 2004 and 31 May 2006 were recorded on electronic case record forms sent to all potential investigators and information about extrapulmonary involvement was collected. Results: One hundred and nineteen of 293 patients (83 female, 36 male, mean age = 45 ± 12 years) had extrapulmonary involvement in this study (40.6%).The median time to diagnosis was 6 months and this was longer than patients with just thoracic sarcoidosis (P = 0.001). Extrapulmonary symptoms were present in 181 (61.8%) patients,and skin lesions, arthralgia and back pain were the commonest (33.4%, 20.8% and 16.4%, respectively). Incidence of organ involvement was independent of age with the exception of ocular involvement, which was higher in those under the age of 40 years (P = 0.007). Conclusions: Skin and peripheral lymph node involvement were the most common sites of extrapulmonary involvement and ocular involvement was more common in those under the age of 40 years in patients with sarcoidosis in a Turkish population. © 2011 The Authors Respirology © 2011 Asian Pacific Society of Respirology. | URI: | https://hdl.handle.net/11499/6053 https://doi.org/10.1111/j.1440-1843.2010.01878.x |
ISSN: | 1323-7799 |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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