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https://hdl.handle.net/11499/6187
Title: | Acute improvement of pulmonary artery pressure by non-invasive positive pressure ventilation in the patients with hypercapnic respiratory failure | Authors: | Dursunoglu, Neşe Dursunoglu, Dursun Moray, A. Gür, Ş. |
Keywords: | Chronic obstructive pulmonary disease Echocardiography Non-invasive positive pressure ventilation Pulmonary arterial pressure Respiratory failure adult arterial pH article assisted ventilation blood gas breathing rate carbon dioxide tension chronic obstructive lung disease clinical article controlled study disease severity Doppler echocardiography female heart failure human hypercapnia hypoxemia lung artery pressure male non invasive positive pressure ventilation physical examination respiratory acidosis respiratory distress respiratory failure treatment outcome Female Humans Hypercapnia Male Middle Aged Positive-Pressure Respiration Pulmonary Artery Pulmonary Disease, Chronic Obstructive Pulmonary Wedge Pressure Respiratory Function Tests Respiratory Insufficiency Treatment Outcome |
Abstract: | It is very important to decrease pulmonary artery pressure (PAP) in patients with chronic obstructive pulmonary disease (COPD) in order to prevent progression to right heart failure. We showed an acute improvement of PAP by non-invasive positive pressure ventilation (NPPV) treatment in patients with hypercapnic respiratory failure. In 26 patients with COPD (18 males and 8 females), physical examination, Doppler echocardiographic evaluation and arterial blood gases analysis were performed on admission and at discharge. PAP was measured by Doppler echocardiography. NPPV was used when 2 of the following were present without contraindications: 1. Respiratory distress with moderate to severe dyspnea, 2. Arterial pH less than 7.35 with PaCO2 above 45 mmHg, 3. Respiratory rate of 25/minute or greater. Mean age of the patients was 62.6 ± 10.8 year, and mean usage of the NPPV was 12.6 ± 5.5 day. Mean and systolic PAPs of the patients (43.8 ± 16.9 mmHg and 66.7 ± 23.3 mmHg) were significantly decreased with NPPV treatment (26.6 ± 8.4 mmHg, p< 0.0001 and 41.8 ± 14.6 mmHg, p< 0.0001). Also, each parameter of the arterial blood gases was improved significantly with NPPV usage. An echocardiographic assessment in the COPD patients having NPPV treatment due to acute respiratory failure, might be a useful and easy method to show an improvement of PAP as a supportive measure in the management of those patients, in addition to beneficial effects of that treatment on respiratory acidosis, hypercapnia and hypoxemia. | URI: | https://hdl.handle.net/11499/6187 | ISSN: | 0494-1373 |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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