Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/6187
Title: Acute improvement of pulmonary artery pressure by non-invasive positive pressure ventilation in the patients with hypercapnic respiratory failure
Authors: Dursunoglu, Neşe
Dursunoglu, Dursun
Moray, A.
Gür, Ş.
Keywords: Chronic obstructive pulmonary disease
Echocardiography
Non-invasive positive pressure ventilation
Pulmonary arterial pressure
Respiratory failure
adult
arterial pH
article
assisted ventilation
blood gas
breathing rate
carbon dioxide tension
chronic obstructive lung disease
clinical article
controlled study
disease severity
Doppler echocardiography
female
heart failure
human
hypercapnia
hypoxemia
lung artery pressure
male
non invasive positive pressure ventilation
physical examination
respiratory acidosis
respiratory distress
respiratory failure
treatment outcome
Female
Humans
Hypercapnia
Male
Middle Aged
Positive-Pressure Respiration
Pulmonary Artery
Pulmonary Disease, Chronic Obstructive
Pulmonary Wedge Pressure
Respiratory Function Tests
Respiratory Insufficiency
Treatment Outcome
Abstract: It is very important to decrease pulmonary artery pressure (PAP) in patients with chronic obstructive pulmonary disease (COPD) in order to prevent progression to right heart failure. We showed an acute improvement of PAP by non-invasive positive pressure ventilation (NPPV) treatment in patients with hypercapnic respiratory failure. In 26 patients with COPD (18 males and 8 females), physical examination, Doppler echocardiographic evaluation and arterial blood gases analysis were performed on admission and at discharge. PAP was measured by Doppler echocardiography. NPPV was used when 2 of the following were present without contraindications: 1. Respiratory distress with moderate to severe dyspnea, 2. Arterial pH less than 7.35 with PaCO2 above 45 mmHg, 3. Respiratory rate of 25/minute or greater. Mean age of the patients was 62.6 ± 10.8 year, and mean usage of the NPPV was 12.6 ± 5.5 day. Mean and systolic PAPs of the patients (43.8 ± 16.9 mmHg and 66.7 ± 23.3 mmHg) were significantly decreased with NPPV treatment (26.6 ± 8.4 mmHg, p< 0.0001 and 41.8 ± 14.6 mmHg, p< 0.0001). Also, each parameter of the arterial blood gases was improved significantly with NPPV usage. An echocardiographic assessment in the COPD patients having NPPV treatment due to acute respiratory failure, might be a useful and easy method to show an improvement of PAP as a supportive measure in the management of those patients, in addition to beneficial effects of that treatment on respiratory acidosis, hypercapnia and hypoxemia.
URI: https://hdl.handle.net/11499/6187
ISSN: 0494-1373
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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