Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/6222
Title: A comparison of spinal anesthesia with low-dose hyperbaric levobupivacaine and hyperbaric bupivacaine for transurethral surgery: A randomized controlled trial
Authors: Erbay, Rıza Hakan
Ermumcu, O.
Hancı, Volkan
Atalay, Habip
Keywords: Anesthesia, Spinal
Hyperbaric levopubivacaine
Transurethral procedures
bupivacaine
ephedrine
fentanyl
levobupivacaine
adult
adverse outcome
aged
anesthesia complication
anesthesia induction
anesthetic recovery
article
dermatome
dose response
double blind procedure
drug effect
drug efficacy
drug quality
female
headache
hemodynamic monitoring
human
hypotension
intraoperative period
low drug dose
major clinical study
male
motor nerve block
nausea
outcome assessment
postoperative analgesia
postoperative pain
pruritus
randomized controlled trial
spinal anesthesia
transurethral resection
vomiting
Adjuvants, Anesthesia
Adolescent
Adult
Aged
Aged, 80 and over
Anesthetics, Local
Bupivacaine
Dose-Response Relationship, Drug
Double-Blind Method
Fentanyl
Hemodynamics
Humans
Male
Middle Aged
Pain Measurement
Pain, Postoperative
Transurethral Resection of Prostate
Treatment Outcome
Young Adult
Abstract: Background. The aim of this study was to compare spinal anesthesia effects of low-dose hyperbaric levobupivacaine and low-dose hyperbaric bupivacaine for transurethral procedures. Methods. In this double-blind, randomized, controlled study, a total of 60 patients who were ASA I-III were randomized into two groups. Group B received 7.5 mg hyperbaric bupivacaine plus 25 µg fentanyl, and Group L received 7.5 mg hyperbaric levobupivacaine plus 25 µg fentanyl intrathecally. The onset time to T10 dermatome, times to maximum sensory and motor block levels, time to two-segment regression of sensory block, time to Bromage score zero, time to full recovery of sensory block, and hemodynamic values, as well as adverse effects, were recorded. The primary outcome was the time to complete regression of motor block. Results. The onset time of block to T10, time to maximum sensory block, and time to two-segment regression were similar in both groups. The time to maximum motor block was shorter in Group B (7 ± 3 min) than in Group L (12±5 min), (P<0.001). The time to a Bromage score of zero (recovery of motor block) was shorter in Group L (105±19 min) than in Group B (113±7 min), (P=0.04). The time to full recovery of sensory block was shorter in Group B (127±14 min) than in Group L (157±34 min), (P<0.001). The requirement for analgesia was earlier in Group B (305±50 min) than in Group L (389±146 min), (P=0.004). Conclusion. Although both techniques provide adequate spinal block and have few similar side effects for transurethral surgery, the use of low-dose hyperbaric levobupivacaine plus fentanyl may be preferable to low-dose hyperbaric bupivacaine plus fentanyl because of the reduced motor block, shorter duration of motor block, longer duration of sensory block and longer time to the first requirement for analgesia.
URI: https://hdl.handle.net/11499/6222
ISSN: 0375-9393
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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