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Title: | Reticulohistiocytosis: Different dermatoscopic faces and a good response to methotrexate treatment: Clinical dermatology • Concise report | Authors: | Kaçar, Nida Tasli, L. Argenziano, G. Demirkan, Neşe |
Keywords: | antinuclear antibody CD68 antigen melanin methotrexate absence of side effects adult article case report dermatofibroma diagnostic value dysphagia epiluminescence microscopy female follow up human hyperpigmentation priority journal reticulohistiocytosis Schirmer test Dermatologic Agents Dermoscopy Female Histiocytosis, Non-Langerhans-Cell Humans Methotrexate Middle Aged |
Abstract: | The reticulohistiocytoses are a rare group of non-Langerhans cell histiocytic disorders. Recently, dermatoscopic features have been reported for some of the xanthomatous disorders. We report a case of diffuse cutaneous reticulohistiocytosis with 29 reticulohistiocytomas. On dermatoscopy of these lesions, we saw three typical features: a homogeneous pattern with various shades of yellow (defined previously as a 'setting-sun' pattern), brown reticular structures, and central white scar-like patches and streaks. The setting-sun pattern was most commonly seen in combination with brown reticular structures. In four lesions, brown reticular structures surrounded a central white scar-like patch resembling that of a dermatofibroma. However, the presence of the setting-sun pattern in the background gave a different hue to that of the peripheral network seen in a dermatofibroma. A marked clinical improvement was associated with 6 months of systemic methotrexate treatment. Dermatoscopy may aid in the diagnosis of xanthomatous diseases. For this patient, methotrexate was beneficial. © 2009 British Association of Dermatologists. | URI: | https://hdl.handle.net/11499/6380 https://doi.org/10.1111/j.1365-2230.2009.03738.x |
ISSN: | 0307-6938 |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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