Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/6393
Title: Determination of 7-ethoxyresorufin-o-deethylase (EROD) induction in leaping mullet (Liza saliens) from the highly contaminated Aliaga Bay, Turkey
Authors: Şen, Alaattin
Ulutas, O.K.
Tutuncu, B.
Ertas, N.
Cok, I.
Keywords: Aliaga Bay
CYP1A1
EROD
Fish
Turkey
Aegean sea
Aquatic environments
Devastating effects
EROD activity
Ethoxyresorufin O-deethylase activities
Ethoxyresorufin-O-deethylase
Industrial activities
Marine organisms
Oil refineries
Reference sites
Sewer discharges
West coast
Aromatic hydrocarbons
Marine biology
Marine pollution
Organic pollutants
Petroleum refineries
Pollution detection
Polycyclic aromatic hydrocarbons
Ships
Biomarkers
cytochrome P450 1A
ethoxyresorufin deethylase
polycyclic aromatic hydrocarbon
biomarker
enzyme activity
fish
immunoassay
industrial waste
marine pollution
organic pollutant
PAH
pollutant source
pollution effect
animal tissue
aquatic environment
article
chemical analysis
immunochemistry
liver
Liza saliens
nonhuman
organic pollution
protein induction
Turkey (republic)
water contamination
water pollution
Animals
Cytochrome P-450 CYP1A1
Environmental Monitoring
Enzyme Induction
Industrial Waste
Liver
Polycyclic Compounds
Smegmamorpha
Water Pollutants, Chemical
Aegean Sea
Izmir [Turkey]
Mediterranean Sea
Abstract: Pollution of the aquatic environment is a global concern owing to the devastating effects of contaminants whose levels are growing at an alarming rate, and it has become a major threat for marine organisms, as well as to humans as consumers. This study has been carried out on leaping mullet obtained from Aliaga Bay, which is located on the west coast of the Aegean Sea near Izmir and hosts the world's fifth largest shipyard, plus a broad range of industrial activities, including an oil refinery and a paper factory. The waste from these industries, combined with municipal sewer discharges, is the main cause of pollution in this region. There is no national documentation or research on the determination of pollution resulting from the industrial activities in this area. In the present study, the degree of induction of CYP4501A-associated 7-ethoxyresorufin O-deethylase (EROD) activity and immunochemical detection of CYP1A1 in the liver of leaping mullet (Lisa saliens) were used as biomarkers for the assessment of polycyclic aromatic hydrocarbon (PAH)-type organic pollutants in Aliaga Bay. Mullet caught from different locations of the bay had approximately 52 times more EROD activity than the feral fish sampled from a clean reference site near Foca, Izmir. The results of this study indicate that Aliaga Bay is highly contaminated with PAH-type organic pollutants. © 2009 Springer Science+Business Media B.V.
URI: https://hdl.handle.net/11499/6393
https://doi.org/10.1007/s10661-009-0928-3
ISSN: 0167-6369
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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