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https://hdl.handle.net/11499/6393
Title: | Determination of 7-ethoxyresorufin-o-deethylase (EROD) induction in leaping mullet (Liza saliens) from the highly contaminated Aliaga Bay, Turkey | Authors: | Şen, Alaattin Ulutas, O.K. Tutuncu, B. Ertas, N. Cok, I. |
Keywords: | Aliaga Bay CYP1A1 EROD Fish Turkey Aegean sea Aquatic environments Devastating effects EROD activity Ethoxyresorufin O-deethylase activities Ethoxyresorufin-O-deethylase Industrial activities Marine organisms Oil refineries Reference sites Sewer discharges West coast Aromatic hydrocarbons Marine biology Marine pollution Organic pollutants Petroleum refineries Pollution detection Polycyclic aromatic hydrocarbons Ships Biomarkers cytochrome P450 1A ethoxyresorufin deethylase polycyclic aromatic hydrocarbon biomarker enzyme activity fish immunoassay industrial waste marine pollution organic pollutant PAH pollutant source pollution effect animal tissue aquatic environment article chemical analysis immunochemistry liver Liza saliens nonhuman organic pollution protein induction Turkey (republic) water contamination water pollution Animals Cytochrome P-450 CYP1A1 Environmental Monitoring Enzyme Induction Industrial Waste Liver Polycyclic Compounds Smegmamorpha Water Pollutants, Chemical Aegean Sea Izmir [Turkey] Mediterranean Sea |
Abstract: | Pollution of the aquatic environment is a global concern owing to the devastating effects of contaminants whose levels are growing at an alarming rate, and it has become a major threat for marine organisms, as well as to humans as consumers. This study has been carried out on leaping mullet obtained from Aliaga Bay, which is located on the west coast of the Aegean Sea near Izmir and hosts the world's fifth largest shipyard, plus a broad range of industrial activities, including an oil refinery and a paper factory. The waste from these industries, combined with municipal sewer discharges, is the main cause of pollution in this region. There is no national documentation or research on the determination of pollution resulting from the industrial activities in this area. In the present study, the degree of induction of CYP4501A-associated 7-ethoxyresorufin O-deethylase (EROD) activity and immunochemical detection of CYP1A1 in the liver of leaping mullet (Lisa saliens) were used as biomarkers for the assessment of polycyclic aromatic hydrocarbon (PAH)-type organic pollutants in Aliaga Bay. Mullet caught from different locations of the bay had approximately 52 times more EROD activity than the feral fish sampled from a clean reference site near Foca, Izmir. The results of this study indicate that Aliaga Bay is highly contaminated with PAH-type organic pollutants. © 2009 Springer Science+Business Media B.V. | URI: | https://hdl.handle.net/11499/6393 https://doi.org/10.1007/s10661-009-0928-3 |
ISSN: | 0167-6369 |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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