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https://hdl.handle.net/11499/6406
Title: | Epidemiology and associated factors for nosocomial methicillin-resistant Staphylococcus aureus infection in a tertiary-care hospital | Authors: | Sacar, S. Sayın Kutlu, Selda Turgut, Hüseyin Cevahir, Nural Hircin Cenger, D. Tekin, K. |
Keywords: | Associated factors MRSA Nosocomial antibiotic agent adolescent adult aged article artificial ventilation bacterial arthritis case control study catheter infection central nervous system infection child female hospital infection hospitalization human infant major clinical study male medical record review methicillin resistant Staphylococcus aureus methicillin resistant Staphylococcus aureus infection newborn omphalitis osteomyelitis pneumonia preschool child retrospective study risk factor school child skin infection soft tissue infection surgical infection tertiary health care urinary tract infection cross infection hospital isolation and purification length of stay microbiology middle aged sex difference Staphylococcus infection surgery Adolescent Adult Aged Aged, 80 and over Case-Control Studies Child Child, Preschool Cross Infection Female Hospitals Humans Infant Infant, Newborn Length of Stay Male Methicillin-Resistant Staphylococcus aureus Middle Aged Respiration, Artificial Retrospective Studies Risk Factors Sex Factors Staphylococcal Infections Surgical Procedures, Operative Young Adult |
Abstract: | We analysed nosocomial MRSA cases between January 2004 and December 2006 in a retrospective case-control study in a 250-bed tertiary-care teaching hospital. During the study period, 265 nosocomial Staphylococcus aureus infections were identified in 231 patients. There was a significant increase in methicillin resistance in isolates (MRSA) from these infections with frequencies for 2004 of 39/88 (443%), 2005 (62/80, 775%), and 2006 (75/97, 773%) (P<0001). Multivariate analysis showed that associated factors for nosocomial MRSA infection were prolonged hospitalization (OR 3982, 95% CI 2235-7094, P<0001), mechanical ventilation (OR 3052, 95% CI 1666-5590, P<0001), surgical operation (OR 2032, 95% CI 1102-3748, P=0023), and male sex (OR 2000, 95% CI 1081-3699, P=0027). The determination of associated factors for methicillin resistance in nosocomial S. aureus infections in hospitals will play an important role in efforts to reduce MRSA infection rates. © Cambridge University Press 2009. | URI: | https://hdl.handle.net/11499/6406 https://doi.org/10.1017/S0950268809991063 |
ISSN: | 0950-2688 |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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