Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/6423
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dc.contributor.authorAkin, F.-
dc.contributor.authorTurgut, Sebahat-
dc.contributor.authorBastemir, M.-
dc.contributor.authorTurgut, Günfer-
dc.contributor.authorKursunluoglu, R.-
dc.contributor.authorKarasu, U.-
dc.contributor.authorGuclu, A.-
dc.date.accessioned2019-08-16T12:07:09Z
dc.date.available2019-08-16T12:07:09Z
dc.date.issued2010-
dc.identifier.issn1044-5498-
dc.identifier.urihttps://hdl.handle.net/11499/6423-
dc.identifier.urihttps://doi.org/10.1089/dna.2009.0934-
dc.description.abstractThe aim of this study was to analyze the distribution of the insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene in obese Turkish patients with insulin resistance (IR). Sixty-two obese Turkish patients with IR were enrolled in this study. One hundred healthy people without IR were recruited as the control group. ACE amplification was performed by polymerase chain reaction. The frequency of the DD genotype was significantly higher in obese patients with IR than in control subjects. Of sixty-two patients, 1 (1.6%) had an II genotype, 22 (35.5%) had an ID genotype, and 39 (62.9%) had a DD genotype. The frequency of the I allele in the patient group was significantly lower than in controls. We found that the frequency of the DD genotype was higher in obese Turkish patients with IR. ACE gene I/D polymorphism may be associated with obesity in the Turkish population. © 2010, Mary Ann Liebert, Inc.en_US
dc.language.isoenen_US
dc.relation.ispartofDNA and Cell Biologyen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectdipeptidyl carboxypeptidaseen_US
dc.subjectACE protein, humanen_US
dc.subjectinsulinen_US
dc.subjectlipiden_US
dc.subjecturic aciden_US
dc.subjectadulten_US
dc.subjectalleleen_US
dc.subjectarticleen_US
dc.subjectcontrolled studyen_US
dc.subjectfemaleen_US
dc.subjectgene deletionen_US
dc.subjectgene frequencyen_US
dc.subjectgene identificationen_US
dc.subjectgene insertionen_US
dc.subjectgenetic associationen_US
dc.subjectgenetic polymorphismen_US
dc.subjectgenotypeen_US
dc.subjecthumanen_US
dc.subjectinsulin resistanceen_US
dc.subjectmajor clinical studyen_US
dc.subjectmaleen_US
dc.subjectobesityen_US
dc.subjectpolymerase chain reactionen_US
dc.subjectpopulation researchen_US
dc.subjectpriority journalen_US
dc.subjectTurkey (republic)en_US
dc.subjectadipose tissueen_US
dc.subjectblooden_US
dc.subjectblood pressureen_US
dc.subjectbody massen_US
dc.subjectgeneticsen_US
dc.subjectglucose blood levelen_US
dc.subjecthistologyen_US
dc.subjectmetabolic syndrome Xen_US
dc.subjectmetabolismen_US
dc.subjectmiddle ageden_US
dc.subjectnon insulin dependent diabetes mellitusen_US
dc.subjectphysiologyen_US
dc.subjectwaist circumferenceen_US
dc.subjectAdipose Tissueen_US
dc.subjectAdulten_US
dc.subjectBlood Glucoseen_US
dc.subjectBlood Pressureen_US
dc.subjectBody Mass Indexen_US
dc.subjectDiabetes Mellitus, Type 2en_US
dc.subjectFemaleen_US
dc.subjectGene Frequencyen_US
dc.subjectGenotypeen_US
dc.subjectHumansen_US
dc.subjectInsulinen_US
dc.subjectInsulin Resistanceen_US
dc.subjectLipidsen_US
dc.subjectMaleen_US
dc.subjectMetabolic Syndrome Xen_US
dc.subjectMiddle Ageden_US
dc.subjectObesityen_US
dc.subjectOverweighten_US
dc.subjectPeptidyl-Dipeptidase Aen_US
dc.subjectPolymorphism, Geneticen_US
dc.subjectTurkeyen_US
dc.subjectUric Aciden_US
dc.subjectWaist Circumferenceen_US
dc.titleAngiotensin-converting enzyme gene polymorphism in overweight and obese Turkish patients with insulin resistanceen_US
dc.typeArticleen_US
dc.identifier.volume29en_US
dc.identifier.issue4en_US
dc.identifier.startpage207
dc.identifier.startpage207en_US
dc.identifier.endpage212en_US
dc.identifier.doi10.1089/dna.2009.0934-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.pmid20070157en_US
dc.identifier.scopus2-s2.0-77951241845en_US
dc.identifier.wosWOS:000276421900007en_US
dc.identifier.scopusqualityQ1-
dc.ownerPamukkale University-
item.openairetypeArticle-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
crisitem.author.dept14.03. Basic Medical Sciences-
crisitem.author.dept14.03. Basic Medical Sciences-
crisitem.author.dept14.02. Internal Medicine-
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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