Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/6498
Title: Transient pulmonary perfusion abnormality after massive exchange transfusion: Case report
Authors: Kılıç, İlknur
ÖzdemIr, Özmert Muhammet Ali
Gürses, Dolunay
Duksal, Fatma
Kıraç, Fatma Suna
Keywords: Exchange transfusion, whole blood
Infant, newborn
Pulmonary diffusing capacity
bilirubin
macrosalb tc 99m
oxygen
article
blood gas analysis
case report
cyanosis
dyspnea
exchange blood transfusion
human
infant
leukocyte aggregation
lung blood vessel
lung dead space
lung gas exchange
lung hemodynamics
lung insufficiency
lung perfusion
lung scintiscanning
lung ventilation
male
newborn jaundice
oxygen saturation
phototherapy
respiratory tract intubation
rhesus isoimmunization
tachypnea
thrombocyte aggregation
treatment indication
vasoconstriction
Publisher: Turkiye Klinikleri
Abstract: The principal indications for exchange transfusion are hemolytic diseases of the newborn with hyperbilirubinemia. However, there are some potential complications of exchange transfusion such as infection, coagulopathies (i.e., thrombocytopenia), electrolyte abnormalities (i.e., hypocalcemia), metabolic acidosis, hypoglycemia, and necrotizing enterocolitis. Stored blood develops some platelet-white cell microaggregates. These microaggregates or blood debris have been found to produce changes in pulmonary hemodynamics in animals and have been implicated in post-traumatic pulmonary insufficiency in man. Authors suggested that pulmonary gas exchange alterations following blood transfusion were primarily due to increased dead-space ventilation secondary to vasoconstriction and occlusion of the pulmonary microvasculature because of microaggregates. In this article, a newborn with transient pulmonary perfusion abnormality who had massive exchange transfusion for Rh isoimmunization and hyperbilirubinemia was reported. © 2010 by Türkiye Klinikleri.
URI: https://hdl.handle.net/11499/6498
https://doi.org/10.5336/medsci.2008-10272
ISSN: 1300-0292
Appears in Collections:Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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