Endometriosis in two sisters with Glanzmann's thrombasthenia

Abstract

Objective: To present two cases of endometriosis in patients with Glanzmann's thrombasthenia (GT) and discuss the underlying pathophysiology of endometriosis. Design: Case report. Setting: Gynecology practice in a university teaching hospital. Patient(s): Two sisters, aged 24 and 28 years, previously diagnosed as having GT. Intervention(s): Surgical exploration. Main Outcome Measure(s): Pathologic examination of surgical specimens was performed. Result(s): A diagnosis of endometriosis was confirmed pathologically for two sisters previously diagnosed as having GT. Conclusion(s): Women with GT seem to represent an important human model of endometriosis from which important data on the pathophysiology of endometriosis can be acquired. © 2009 American Society for Reproductive Medicine.