Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/6952
Title: Serological and entomological survey of zoonotic visceral leishmaniasis in Denizli Province, Aegean Region, Turkey
Authors: Töz, S.Ö.
Sakru, N.
Ertabaklar, H.
Demir, S.
Şengül, Mustafa
Ozbel, Y.
Keywords: Canine
Human
Leishmaniasis
Sand flies
Visceral
Western Turkey
protozoon antibody
adult
animal
article
blood
child
classification
disease carrier
disease transmission
dog
dog disease
female
human
leishmaniasis
male
parasitology
Phlebotomus
physiology
prevalence
Turkey (republic)
visceral leishmaniasis
zoonosis
Adult
Animals
Antibodies, Protozoan
Child
Dog Diseases
Dogs
Female
Humans
Insect Vectors
Leishmaniasis, Visceral
Male
Prevalence
Turkey
Zoonoses
Canis familiaris
Phlebotominae
Phlebotomus neglectus
Phlebotomus papatasi
Abstract: A cross-sectional seroepidemiological survey of leishmaniasis was carried out among children and adults from four villages and one district of Denizli province located in the Southern Aegean Region of Turkey where 14 human visceral leishmaniasis (HVL) cases including 4 adults were reported between 1993 and 2000. Blood samples were taken from 329 children, 217 adults and 140 dogs and a physical examination was also done. Indirect fluorescent antibody test and enzyme linked immunosorbent assay were performed for all sera. All 329 sera collected from children were found to be negative while 2 (0.09%) out of 217 adult sera were found to be seropositive. One seropositive adult patient was confirmed parasitologically as HVL after bone marrow aspiration and treated with AmBisome® while the other was followed only serologically because of the absence of symptoms. The overall canine leishmaniasis seroprevalence was found to be 20.7%. Sand flies were collected using CDC light traps in three out of five study sites and midguts of females were checked for promastigotes after dissection/identification. Eight Phlebotomus species were found in the region. Phlebotomus neglectus and P. papatasi were determined as dominant species with the ratio of 43.52% and 37.35%, respectively. No promastigotes were found in the midgut specimens. In addition, the results showed the presence of vector sand fly species, as well as a high seroprevalence of anti-Leishmania antibodies among dogs from rural and a suburban area of Denizli province with a large proportion of asymptomatic seropositive dogs.
URI: https://hdl.handle.net/11499/6952
ISSN: 1121-7138
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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